Department of General Surgery, Institute of Health Sciences Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara-Turkey.
Department of General Surgery, Institute of Health Sciences, Gülhane Training and Research Hospital, Ankara-Turkey.
Ulus Travma Acil Cerrahi Derg. 2022 Mar;28(3):262-267. doi: 10.14744/tjtes.2020.68202.
There are various surgical and invasive treatment systems such as conservative skin grafts and autologous epider-mal grafting (AEG) for diabetic foot ulcers. This study aims to evaluate the feasibility of using a novel epidermal graft harvesting system in diabetic foot ulcer emergencies.
A retrospective clinical study was conducted with 15 diabetic foot ulcer patients, and after written and signed consent forms were taken, AEG system was applied to all patients. All of the clinical data of the patients such as their American Society of Anesthesiologists (ASA) Physical Status Classification System scores, size of pre-application wound area (cm2), time to complete re-epithelization of the wound, pain scores using the visual analog scale (VAS) for both donor and recipient sites, changes in size of wound, complete dermal response time, and patients' demographics, comorbidities were recorded. The age, gender, pre-post appli-cation wound area (cm2), time of healing, ASA, and VAS variables were compared each other and analyzed statistically. P<0.05 was considered as statistically significant.
The mean of time for complete wound healing was 5.9 (range 4-8) weeks. There was no statistically difference between recipient wound size and patient's age; size of both types of wounds (cm2) and time (weeks) for complete reduction for both types of wounds; and time to complete both types of wound healing and gender (p=0.509, 0.788, and 0.233, respectively). ASA scores did not impact the time required for complete healing of the wound (p=0.749).
The current study has tried to evaluate the efficacy of the AEG system in a homogenous population with diabetic foot ulcers. An epidermal harvesting system may be used effectively and safely in patients with diabetic foot ulcer emergencies.
对于糖尿病足溃疡，有各种手术和侵入性治疗系统，如保守的皮肤移植和自体表皮移植（AEG）。本研究旨在评估新型表皮移植采集系统在糖尿病足溃疡急症中的应用可行性。
对 15 例糖尿病足溃疡患者进行回顾性临床研究，在取得书面和签署的同意书后，对所有患者应用 AEG 系统。记录所有患者的临床资料，如美国麻醉医师协会（ASA）身体状况分类系统评分、应用前创面面积（cm2）、创面完全上皮化时间、供区和受区的视觉模拟评分（VAS）疼痛评分、创面大小变化、完全真皮反应时间以及患者的人口统计学、合并症。比较年龄、性别、应用前后创面面积（cm2）、愈合时间、ASA 和 VAS 变量，并进行统计学分析。P<0.05 为统计学差异有意义。
创面完全愈合的平均时间为 5.9（4-8）周。受区创面大小与患者年龄之间无统计学差异；两种类型创面的面积（cm2）和完全缩小所需时间（周）；以及两种类型创面完全愈合时间和性别（p=0.509、0.788 和 0.233）之间无统计学差异。ASA 评分不影响创面完全愈合所需时间（p=0.749）。
本研究试图在糖尿病足溃疡同质人群中评估 AEG 系统的疗效。表皮采集系统可安全有效地应用于糖尿病足溃疡急症患者。
