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[一名患有严重腹泻、营养不良和急性肾衰竭患者的胶原性口炎性腹泻]

[Collagenous sprue in a patient with severe diarrhoea, malnutrition and acute renal failure].

作者信息

Hallan Andreas, Jensen Michael Dam, Hagemann-Madsen Rikke Hjarnø, Nathan Torben

机构信息

Afdeling for Medicinske Mavetarmsygdomme, Odense Universitetshospital.

Gastroenterologisk Sektion, Medicinsk Afdeling, Sygehus Lillebælt, Vejle.

出版信息

Ugeskr Laeger. 2022 Apr 18;184(16).

Abstract

Collagenous sprue is a rare enteropathy affecting the small intestinal mucosa and can resemble and coincide with coeliac disease or collagenous colitis. To our knowledge, less than 175 cases of collagenous sprue have been described. Both clinicians and pathologists should be aware of the condition in order to adequately target their investigations and treatment. This is a case report of severe collagenous sprue in a 78-year-old male resulting in severe diarrhoea, weight loss, malnutrition and acute kidney failure. The disorder improved on a lactose and gluten-free diet, loperamide and corticosteroids.

摘要

胶原性口炎性腹泻是一种罕见的影响小肠黏膜的肠病,可类似于乳糜泻或胶原性结肠炎并与之同时存在。据我们所知,已报道的胶原性口炎性腹泻病例不足175例。临床医生和病理学家均应了解这种疾病,以便有针对性地进行检查和治疗。本文报告一例78岁男性的严重胶原性口炎性腹泻病例,该病例导致严重腹泻、体重减轻、营养不良和急性肾衰竭。该疾病在采用无乳糖和无麸质饮食、洛哌丁胺及皮质类固醇治疗后有所改善。

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