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产前保健扩张与妊娠期拉丁裔紧急医疗补助受助人中妊娠糖尿病使用抗糖尿病药物的关联。

Association of Prenatal Care Expansion With Use of Antidiabetic Agents During Pregnancies Among Latina Emergency Medicaid Recipients With Gestational Diabetes.

机构信息

Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland.

Center for Health Systems Effectiveness, Oregon Health & Science University, Portland.

出版信息

JAMA Netw Open. 2022 Apr 1;5(4):e229562. doi: 10.1001/jamanetworkopen.2022.9562.

Abstract

IMPORTANCE

Access to necessary prenatal care is not guaranteed through Medicaid for some people with low income based on their immigration status. Although states have the option to extend emergency Medicaid coverage for prenatal care, many states have not expanded coverage.

OBJECTIVE

To evaluate whether the receipt of prenatal care services through the extension of emergency Medicaid coverage is associated with an increase in antidiabetic medication use among Latina patients with gestational diabetes.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study used linked Medicaid claims and birth certificate data on live births to 4869 Latina patients from October 1, 2010, to December 31, 2019, with a difference-in-differences design to compare the rollout of prenatal care and services in Oregon in 2013 with a comparison state, South Carolina, that did not cover prenatal or postpartum care.

EXPOSURE

Medicaid coverage of prenatal care.

MAIN OUTCOMES AND MEASURES

The main outcome was the receipt of antidiabetic agents. Secondary outcomes included hypertensive disorders, cesarean delivery, postpartum contraception, and a newborn morbidity composite outcome (large size for gestational age, neonatal intensive care unit admission, and preterm birth).

RESULTS

The study sample included live births to 4869 Latina patients (mean [SD] age, 32.7 [5.5] years [range, 12-44 years]) enrolled in emergency Medicaid who were mainly aged 25 to 34 years (1499 of 2907 [51.6%]), multiparous (2626 of 2907 [90.3%]), and living in urban areas (2299 of 2907 [79.1%]). After Oregon's policy change to offer prenatal coverage to individuals receiving emergency Medicaid, there was a large and significant increase in the receipt of antidiabetic agents among all people with diabetes during pregnancy (gestational diabetes). Prior to the policy, only 0.3% of all Latina emergency Medicaid recipients with gestational diabetes (2 of 617) received any medication (oral agents or insulin) to manage their blood glucose level. After the policy change, 28.8% of all patients with gestational diabetes (295 of 1023) received medication to manage their blood glucose level, translating to a 27.9-percentage-point increase (95% CI, 24.5-31.2 percentage points) in the receipt of antidiabetic agents in the adjusted model. The policy was also associated with a 10.4-percentage-point (95% CI, 5.3-15.5 percentage points) increase in insulin use during pregnancy among all patients with gestational diabetes. We observed an increase in postpartum contraceptive use (21.2 percentage points; 95% CI, 14.9-27.5 percentage points), the majority of which was due to postpartum sterilization (increase of 16.1 percentage points; 95% CI, 10.4-21.8 percentage points). We did not observe a significant association with gestational hypertension, cesarean births, or newborn health.

CONCLUSIONS AND RELEVANCE

This retrospective cohort study suggests that expanded emergency Medicaid benefits that included prenatal care were associated with an increased use of antidiabetic medications and postpartum contraception during pregnancy.

摘要

重要提示

根据移民身份的不同,一些低收入人群无法通过医疗补助计划获得必要的产前护理。尽管各州有权扩大紧急医疗补助计划中产前护理的覆盖范围,但许多州并未扩大覆盖范围。

目的

评估扩大紧急医疗补助计划中产前护理的覆盖范围是否会增加拉丁裔妊娠糖尿病患者使用抗糖尿病药物的情况。

设计、地点和参与者:本队列研究使用了 2010 年 10 月 1 日至 2019 年 12 月 31 日期间连接的医疗补助索赔和出生证明数据,对来自俄勒冈州的 4869 名拉丁裔患者(2907 名女性中有 4869 名)进行了评估,使用差分设计比较了俄勒冈州在 2013 年与未覆盖产前或产后护理的比较州南卡罗来纳州之间的产前护理和服务的推出情况。

暴露因素

医疗补助计划覆盖产前护理。

主要结果和测量指标

主要结果是接受抗糖尿病药物治疗的情况。次要结果包括高血压疾病、剖宫产、产后避孕以及新生儿发病率综合结果(巨大儿、新生儿重症监护病房入院和早产)。

结果

研究样本包括接受紧急医疗补助的 4869 名拉丁裔患者(平均[标准差]年龄为 32.7[5.5]岁[范围为 12-44 岁])的活产,主要年龄在 25 至 34 岁(1499 名中的 2907 名[51.6%]),多胎(2626 名中的 2907 名[90.3%]),居住在城市地区(2299 名中的 2907 名[79.1%])。在俄勒冈州改变政策为接受紧急医疗补助的个人提供产前护理后,所有妊娠糖尿病患者(妊娠期糖尿病)接受抗糖尿病药物治疗的比例大幅显著增加。在政策实施之前,只有 0.3%的所有患有妊娠糖尿病的拉丁裔紧急医疗补助受助人(617 名中的 2 名)接受任何药物(口服药物或胰岛素)来控制血糖水平。在政策改变后,28.8%的所有妊娠糖尿病患者(1023 名中的 295 名)接受了药物来控制血糖水平,这意味着在调整后的模型中,接受抗糖尿病药物治疗的比例增加了 27.9 个百分点(95%置信区间,24.5-31.2 个百分点)。该政策还与所有妊娠糖尿病患者胰岛素使用量增加了 10.4 个百分点(95%置信区间,5.3-15.5 个百分点)有关。我们观察到产后避孕使用量增加(21.2 个百分点;95%置信区间,14.9-27.5 个百分点),其中大部分是由于产后绝育(增加 16.1 个百分点;95%置信区间,10.4-21.8 个百分点)。我们没有发现与妊娠高血压、剖宫产或新生儿健康有显著关联。

结论和相关性

这项回顾性队列研究表明,扩大紧急医疗补助计划中包括产前护理的福利与妊娠期间抗糖尿病药物和产后避孕的使用增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f49d/9055460/f63ed8946a43/jamanetwopen-e229562-g001.jpg

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