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Lipid-based nanoparticles: advancing therapeutic strategies for vitiligo management.
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Discrete Immolative Guanidinium Transporters deliver mRNA to specific organs and red blood cells.
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Lipid nanoparticle-delivered IFNα2 activates Cxcl9 to increase T cell tumor recruitment to suppress lung metastasis.
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The secret life of RNA and lipids.
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Enhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation.
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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.
Nat Immunol. 2022 Apr;23(4):532-542. doi: 10.1038/s41590-022-01160-y. Epub 2022 Mar 24.
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The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory.
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From lipids to lipid nanoparticles to mRNA vaccines.
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The tangled history of mRNA vaccines.
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Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines.
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Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.
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The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation.
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