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腹腔镜与开放手术治疗十二指肠闭锁的比较:一项 NSQIP-儿科分析。

Laparoscopic Versus Open Surgical Repair of Duodenal Atresia: A NSQIP-Pediatric Analysis.

机构信息

Division of General Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Children's Center, Baltimore, Maryland.

Division of General Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Children's Center, Baltimore, Maryland.

出版信息

J Surg Res. 2022 Nov;279:803-808. doi: 10.1016/j.jss.2022.04.028. Epub 2022 Apr 27.

Abstract

INTRODUCTION

Laparoscopic repair of duodenal atresia in neonates has gained popularity among some pediatric surgeons. Single-center studies suggest comparable short-term outcomes to open surgery. The purpose of this study was to utilize a large, multi-institutional pediatric dataset to examine 30-day post-operative outcomes by operative approach for newborns who underwent duodenal atresia repairs.

METHODS

We identified neonates aged ≤1 wk in the 2016-2018 National Surgical Quality Improvement Program-Pediatric -database that underwent a laparoscopic or open repair for duodenal atresia. Preoperative characteristics were compared between operative approaches. Postoperative complications, operative time, postoperative length of stay (LOS), and supplemental nutrition at discharge were assessed using multivariate regressions.

RESULTS

There were 267 neonates who met inclusion criteria. There were 233 (87%) infants who underwent open repairs and 34 (13%) who underwent laparoscopic repairs. Ten (29%) children who had laparoscopy were converted to open. After adjusting for confounding, laparoscopy was associated with an increase in operative time by 65 min (95% confidence interval 45-87 min, P < 0.001) but a five-day shorter LOS (95% confidence interval -9 to -2, P = 0.006) when compared to laparotomy. There were no significant differences in postoperative complications or supplemental nutrition at discharge.

CONCLUSIONS

Our findings suggest that laparoscopic repairs of duodenal atresia are associated with shorter postoperative LOS but longer operative times when compared to open repairs. Although the conversion rate to laparotomy remained relatively high, the laparoscopic approach was associated with comparable 30-day postoperative outcomes.

摘要

简介

腹腔镜修复新生儿十二指肠闭锁在一些小儿外科医生中越来越受欢迎。单中心研究表明,其短期结果与开放手术相当。本研究的目的是利用一个大型多机构儿科数据集,通过手术方式检查接受十二指肠闭锁修复的新生儿术后 30 天的术后结果。

方法

我们在 2016-2018 年国家手术质量改进计划-小儿数据库中确定了年龄≤1 周的新生儿,他们接受了腹腔镜或开放手术修复十二指肠闭锁。比较了两种手术方法的术前特征。使用多元回归评估术后并发症、手术时间、术后住院时间(LOS)和出院时补充营养情况。

结果

共有 267 名符合纳入标准的新生儿。233 名(87%)婴儿接受了开放修复,34 名(13%)接受了腹腔镜修复。10 名(29%)接受腹腔镜的患儿转为开放。在调整混杂因素后,与剖腹手术相比,腹腔镜手术的手术时间增加了 65 分钟(95%置信区间 45-87 分钟,P < 0.001),但 LOS 缩短了 5 天(95%置信区间 -9 至-2,P = 0.006)。术后并发症或出院时补充营养方面无显著差异。

结论

我们的研究结果表明,与剖腹手术相比,腹腔镜修复十二指肠闭锁与术后 LOS 缩短但手术时间延长有关。尽管转为剖腹手术的比率仍然相对较高,但腹腔镜方法与可比的 30 天术后结果相关。

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