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Membrane adsorption in vancomycin treatment is membrane type dependent in CVVHDF: dose correction is crucial.在连续性静脉-静脉血液透析滤过（CVVHDF）中，万古霉素治疗中的膜吸附取决于膜的类型：剂量校正至关重要。
Crit Care. 2022 Apr 29;26(1):117. doi: 10.1186/s13054-022-03991-5.
2
Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous haemodiafiltration (CVVHDF).探讨连续静脉-静脉血液透析滤过（CVVHDF）治疗患者万古霉素的群体药动学模型。
Crit Care. 2021 Dec 20;25(1):443. doi: 10.1186/s13054-021-03863-4.
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Contribution of diafiltration and adsorption to vancomycin clearance in a continuous hemodiafiltration circuit model in vitro.在体外连续血液透析滤过模型中，对流和吸附对万古霉素清除率的贡献。
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Augmented teicoplanin clearance through probable adsorption onto a polymethyl methacrylate (PMMA) hemofilter during continuous venovenous hemodiafiltration.在连续静脉-静脉血液透析滤过过程中，可能通过吸附到聚甲基丙烯酸甲酯（PMMA）血滤器上而增强替考拉宁的清除率。
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Factors affecting serum concentration of vancomycin in critically ill oliguric pediatric patients receiving continuous venovenous hemodiafiltration.影响连续性静脉-静脉血液透析滤过治疗少尿危重症患儿血药浓度的因素。
PLoS One. 2018 Jun 21;13(6):e0199158. doi: 10.1371/journal.pone.0199158. eCollection 2018.
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Population pharmacokinetic analysis of vancomycin in pediatric continuous renal replacement therapy.儿童连续性肾脏替代治疗中万古霉素的群体药代动力学分析。
Eur J Clin Pharmacol. 2019 Aug;75(8):1089-1097. doi: 10.1007/s00228-019-02664-7. Epub 2019 Apr 1.
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Molecular adsorbent recirculating system (MARS) and continuous veno-venous hemodiafiltration (CVVHDF) for diltiazem removal: An in vitro study.分子吸附再循环系统（MARS）和连续静脉-静脉血液透析滤过（CVVHDF）清除地尔硫䓬：一项体外研究。
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Vancomycin pharmacokinetics in critically ill patients receiving continuous venovenous haemodiafiltration.接受连续性静脉-静脉血液透析滤过的危重症患者的万古霉素药代动力学
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Adsorption of vancomycin, gentamycin, ciprofloxacin and tygecycline on the filters in continuous renal replacement therapy circuits: in full blood in vitro study.万古霉素、庆大霉素、环丙沙星和替加环素在连续肾脏替代治疗回路中的过滤器上的吸附：全血体外研究。
J Artif Organs. 2021 Mar;24(1):65-73. doi: 10.1007/s10047-020-01214-8. Epub 2020 Oct 8.
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Clearance of linezolid via continuous venovenous hemodiafiltration.利奈唑胺通过持续静静脉血液透析滤过的清除率。
Am J Kidney Dis. 2006 Jun;47(6):e83-6. doi: 10.1053/j.ajkd.2006.03.037.

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1
Vancomycin Sequestration in ST Filters: An In Vitro Study.万古霉素在ST过滤器中的潴留：一项体外研究
Antibiotics (Basel). 2023 Mar 21;12(3):620. doi: 10.3390/antibiotics12030620.
2
Effect of Continuous Renal Replacement Therapy with the oXiris Hemofilter on Critically Ill Patients: A Narrative Review.采用oXiris血液滤过器进行持续肾脏替代治疗对重症患者的影响：一项叙述性综述。
J Clin Med. 2022 Nov 13;11(22):6719. doi: 10.3390/jcm11226719.

本文引用的文献

1
Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous haemodiafiltration (CVVHDF).探讨连续静脉-静脉血液透析滤过（CVVHDF）治疗患者万古霉素的群体药动学模型。
Crit Care. 2021 Dec 20;25(1):443. doi: 10.1186/s13054-021-03863-4.
2
Comparison of adsorption of selected antibiotics on the filters in continuous renal replacement therapy circuits: in vitro studies.连续肾脏替代治疗回路中选定抗生素在滤器上的吸附比较：体外研究
J Artif Organs. 2020 Jun;23(2):163-170. doi: 10.1007/s10047-019-01139-x. Epub 2019 Oct 20.
3
Newly designed CRRT membranes for sepsis and SIRS--a pragmatic approach for bedside intensivists summarizing the more recent advances: a systematic structured review.新型 CRRT 膜在脓毒症和 SIRS 中的应用——床边重症监护医师实用方法综述：系统的结构化综述。
ASAIO J. 2013 Mar-Apr;59(2):99-106. doi: 10.1097/MAT.0b013e3182816a75.
4
Principles of antibacterial dosing in continuous renal replacement therapy.连续性肾脏替代治疗中抗菌药物给药的原则。
Crit Care Med. 2009 Jul;37(7):2268-82. doi: 10.1097/CCM.0b013e3181aab3d0.
5
The adsorption of vancomycin by polyacrylonitrile, polyamide, and polysulfone hemofilters.万古霉素在聚丙烯腈、聚酰胺和聚砜血液滤过器上的吸附作用。
Artif Organs. 2008 Jan;32(1):81-4. doi: 10.1111/j.1525-1594.2007.00460.x.

Membrane adsorption in vancomycin treatment is membrane type dependent in CVVHDF: dose correction is crucial.

作者信息

Honore Patrick M, Redant Sebastien, Djimafo Pharan, Preseau Thierry, Cismas Bogdan Vasile, Kaefer Keitiane, Barreto Gutierrez Leonel, Anane Sami, Attou Rachid, Gallerani Andrea, De Bels David

机构信息

ICU Department, Centre Hospitalier Universitaire Brugmann-Brugmann University Hospital, Place Van Gehuchtenplein, 4, 1020, Brussels, Belgium.

ED Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium.

出版信息

Crit Care. 2022 Apr 29;26(1):117. doi: 10.1186/s13054-022-03991-5.

DOI:10.1186/s13054-022-03991-5
PMID:35488349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9052574/
Abstract
摘要