Tarutta E P, Milash S V, Epishina M V, Eliseeva E K
Helmholtz National Medical Research Center of Eye Diseases, Moscow, Russia.
Vestn Oftalmol. 2022;138(2):16-22. doi: 10.17116/oftalma202213802116.
To study the changes in subfoveal choroidal thickness in children with progressive myopia who have been wearing bifocal soft contact lenses (BSCL) with an ADD power of +4.0 D for 3 months.
The study included 40 patients (80 eyes) with progressive myopia of low and moderate degrees. The main group consisted of 23 patients aged 10.04±1.5 years with an average myopia of -3.06±1.17 D, they were examined before and 3 months after vision correction with bifocal soft contact lenses Prima BIO Bi-focal («OkVision Retail», Russia). The control group consisted of 17 patients (34 eyes) aged 9.29±0.92 years with an average myopia of -3.05±1.5 D using single vision spectacle lenses. Cycloplegic refraction, choroidal thickness and axial length were measured in all patients before and after 3 months. Choroidal thickness was measured using the semi-automatic method on the optical coherent tomography system RS-3000 Advance 2 («Nidek», Japan). Axial length was measured using the optical biometer IOL Master 500 («Carl Zeiss», Germany).
In the main group, subfoveolar choroidal thickness increased on average by 15.3±24.3 μm after 3 months of wearing BSCL, and in the control group it decreased on average by 9.03±28.65 μm. Comparison of changes in choroidal thickness between the main and the control groups revealed a significant difference (<0.001). Increase in axial length of the eye in the main group was significantly less than in the control group (0.005±0.08 mm vs 0.07±0.06 mm; <0.001). A strong negative correlation was found between changes in the axial length and subfoveolar choroidal thickness in the main group (= -0.67), but no similar relationship was found in the control group (= -0.13).
Subfoveolar choroidal thickness increases in children wearing bifocal soft contact lenses for myopia correction.
研究佩戴附加光度为+4.0D的双焦点软性接触镜(BSCL)3个月的进展性近视儿童黄斑中心凹下脉络膜厚度的变化。
本研究纳入40例(80只眼)低中度进展性近视患者。主要组由23例年龄为10.04±1.5岁、平均近视度数为-3.06±1.17D的患者组成,他们在使用Prima BIO双焦点软性接触镜(“OkVision Retail”,俄罗斯)进行视力矫正前及矫正3个月后接受检查。对照组由17例(34只眼)年龄为9.29±0.92岁、平均近视度数为-3.05±1.5D的患者组成,他们使用单焦点眼镜片。在所有患者3个月前后测量睫状肌麻痹验光、脉络膜厚度和眼轴长度。脉络膜厚度采用半自动方法在光学相干断层扫描系统RS-3000 Advance 2(“尼德克”,日本)上进行测量。眼轴长度采用光学生物测量仪IOL Master 500(“卡尔蔡司”,德国)进行测量。
在主要组中,佩戴BSCL 3个月后黄斑中心凹下脉络膜厚度平均增加15.3±24.3μm,而在对照组中平均减少9.03±28.65μm。主要组与对照组脉络膜厚度变化的比较显示出显著差异(<0.001)。主要组眼轴长度的增加明显小于对照组(0.005±0.08mm对0.07±0.06mm;<0.001)。在主要组中发现眼轴长度变化与黄斑中心凹下脉络膜厚度之间存在强负相关(=-0.67),但在对照组中未发现类似关系(=-0.13)。
佩戴双焦点软性接触镜矫正近视的儿童黄斑中心凹下脉络膜厚度增加。