Hulsbosch Lianne P, Boekhorst Myrthe Gbm, Endendijk Joyce, Nyklíček Ivan, Potharst Eva S, Pop Victor Jm
Center of Research in Psychological and Somatic Disorders (CoRPS), Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands.
Child and Adolescent Studies, Utrecht University, Utrecht, the Netherlands.
J Psychiatr Res. 2022 Jul;151:166-172. doi: 10.1016/j.jpsychires.2022.04.023. Epub 2022 Apr 25.
Exploring possible protective factors against antenatal depression is important since antenatal depression is common and affects both mother and child. The person characteristic trait mindfulness may be such a protective factor. Because of the high variability in depressive symptoms over time, we aimed to assess the association between trait mindfulness and trajectories of depressive symptoms during pregnancy.
A subsample of 762 women participating in the HAPPY study completed the Three Facet Mindfulness Questionnaire-Short Form at 22 weeks of pregnancy. Possible different trajectories of Edinburgh Postnatal Depression Scale (EPDS) scores, assessed at each pregnancy trimester, were explored with growth mixture modeling.
Three EPDS trajectories (classes) were identified: low stable symptom scores (N = 607, 79.7%), decreasing symptom scores (N = 74, 9.7%) and increasing symptom scores (N = 81, 10.6%). Compared to belonging to the low stable class (reference), women with higher scores on the trait mindfulness facets 'acting with awareness' and 'non-judging' were less likely to belong to the decreasing class (OR = 0.81, 95% CI [0.73, 0.90] and OR = 0.77, 95% CI [0.70, 0.84]) and increasing class (OR = 0.88, 95% CI [0.80, 0.97] and OR = 0.72, 95% CI [0.65, 0.79]). Women with higher scores on 'non-reacting' were less likely to belong to the increasing class (OR = 0.89, 95% CI [0.82, 0.97]), but not the decreasing class (OR = 0.96, 95% CI [0.87, 1.04]). All analyses were adjusted for confounders.
Characteristics of trait mindfulness predicted low stable levels of depressive symptoms throughout pregnancy. Mindfulness-based programs may be beneficial for pregnant women as a strategy to alleviate depression risks.
鉴于产前抑郁很常见且会影响母婴双方，探寻可能的产前抑郁保护因素十分重要。个体特质正念可能就是这样一种保护因素。由于抑郁症状随时间变化差异很大，我们旨在评估特质正念与孕期抑郁症状轨迹之间的关联。
参与HAPPY研究的762名女性子样本在妊娠22周时完成了三因素正念问卷简表。采用生长混合模型探讨了在每个孕期评估的爱丁堡产后抑郁量表（EPDS）得分可能存在的不同轨迹。
确定了三种EPDS轨迹（类别）：低且稳定的症状得分（N = 607，79.7%）、症状得分下降（N = 74，9.7%）和症状得分上升（N = 81，10.6%）。与属于低且稳定类别（参照）相比，在特质正念方面“有意识行动”和“不评判”得分较高的女性属于症状得分下降类别的可能性较小（比值比[OR]=0.81，95%置信区间[CI][0.73，0.90]；OR = 0.77，95% CI[0.70，0.84]），属于症状得分上升类别的可能性也较小（OR = 0.88，95% CI[0.80，0.97]；OR = 0.72，95% CI[0.65，0.79]）。“不反应”得分较高的女性属于症状得分上升类别的可能性较小（OR = 0.89，95% CI[0.82，0.97]），但属于症状得分下降类别的可能性未降低（OR = 0.96，95% CI[0.87，1.04]）。所有分析均对混杂因素进行了校正。
特质正念的特征预示着整个孕期抑郁症状处于低且稳定的水平。基于正念的项目作为减轻抑郁风险的策略，可能对孕妇有益。
