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小儿心脏手术中双侧竖脊肌平面阻滞:一项随机对照研究。

Bilateral erector spinae plane blocks in children undergoing cardiac surgery: A randomized, controlled study.

机构信息

Department of Anesthesiology and Reanimation, Çukurova University, Adana, Turkey.

Department of Anesthesiology and Reanimation, Çukurova University, Adana, Turkey.

出版信息

J Clin Anesth. 2022 Sep;80:110797. doi: 10.1016/j.jclinane.2022.110797. Epub 2022 Apr 28.

Abstract

STUDY OBJECTIVE

We aimed to test the hypothesis that erector spinae plane block (ESPB) provides efficient analgesia and reduces postoperative morphine consumption in children undergoing cardiac surgery with median sternotomy.

DESIGN

A prospective, blinded, randomized, controlled study.

SETTING

A tertiary university hospital, operating room and intensive care unit.

PATIENTS

Forty children aged 2-10 years, who underwent cardiac surgery with median sternotomy. The patients were randomly divided into the block group (Group B) and the control group (Group C).

INTERVENTIONS

Group B (n = 20) were treated with ultrasound-guided bilateral ESPB at the level of the T4-T5 transverse process, whereas no block was administered in Group C (n = 20). In all children, intravenous morphine at 0.05 mg/kg was used whenever the modified objective pain score (MOPS) ≥4 for postoperative analgesia.

MEASUREMENTS

The MOPS and Ramsay sedation score (RSS) were assessed at 0, 1, 2, 4, 6, 8, 10, 12, 16, 20 and 24 h postoperatively. Total morphine consumption at 24 h, extubation time and length of intensive care unit (ICU) stay was also evaluated and recorded.

MAIN RESULTS

Bilateral ESPB significantly decreased the consumption of morphine in the first 24 h, postoperatively. During the postoperative 24-h follow-up, 11 children in Group C requested morphine and the cumulative dose of morphine was 0.83 ± 0.91 mg, while 4 children in Group B requested morphine and the cumulative dose of morphine was 0.26 ± 0.59 mg (p = 0.043). There was no significant difference between Groups B and C in terms of MOPS and RSS values, extubation time or length of ICU stay.

CONCLUSION

Ultrasound-guided bilateral ESPB with bupivacaine provides efficient postoperative analgesia and reduces postoperative morphine consumption at 24 h in children undergoing cardiac surgery.

摘要

研究目的

我们旨在检验这样一个假设,即竖脊肌平面阻滞(ESPB)可为经正中胸骨切开术行心脏手术的儿童提供有效的镇痛,并减少术后吗啡的用量。

设计

前瞻性、盲法、随机、对照研究。

地点

一所三级大学医院的手术室和重症监护病房。

患者

40 名年龄在 2-10 岁、行正中胸骨切开术的心脏手术患儿。患者被随机分为阻滞组(B 组)和对照组(C 组)。

干预措施

B 组(n=20)在 T4-T5 横突水平接受超声引导下双侧 ESPB,而 C 组(n=20)未接受阻滞。所有患儿在术后改良客观疼痛评分(MOPS)≥4 时,均给予静脉注射吗啡 0.05mg/kg 以进行术后镇痛。

测量

术后 0、1、2、4、6、8、10、12、16、20 和 24 小时评估并记录 MOPS 和 Ramsay 镇静评分(RSS)。还评估和记录了 24 小时内吗啡总消耗量、拔管时间和重症监护病房(ICU)住院时间。

主要结果

双侧 ESPB 可显著减少术后 24 小时内吗啡的用量。在术后 24 小时的随访期间,C 组 11 名患儿要求使用吗啡,累积吗啡剂量为 0.83±0.91mg,而 B 组 4 名患儿要求使用吗啡,累积吗啡剂量为 0.26±0.59mg(p=0.043)。B 组和 C 组在 MOPS 和 RSS 值、拔管时间或 ICU 住院时间方面无显著差异。

结论

布比卡因超声引导下双侧 ESPB 可为经正中胸骨切开术行心脏手术的儿童提供有效的术后镇痛,并减少术后 24 小时内吗啡的用量。

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