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双侧超声引导竖脊肌平面阻滞用于接受后路脊柱融合术的小儿特发性脊柱侧凸患者的术后镇痛:一项随机对照试验。

Bilateral ultrasound-guided erector spinae plane block for postoperative analgesia in paediatric idiopathic scoliosis patients undergoing posterior spine fusion surgery: a randomized controlled trial.

机构信息

Department of Anaesthesiology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56, South Lishi Road, Beijing, 100045, China.

Department of Orthopaedics, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

出版信息

Eur Spine J. 2024 Oct;33(10):3823-3832. doi: 10.1007/s00586-024-08457-6. Epub 2024 Aug 22.

Abstract

PURPOSE

Major spinal surgery causes severe pain. We examined the ability of erector spinae plane block (ESPB) to alleviate pain after posterior spinal fusion (PSF) in paediatric scoliosis patients.

METHODS

Seventy-two patients who underwent PSF were randomized into a preoperative ultrasound-guided ESPB group or a no-block control group. The composite primary outcome was the area under the curve (AUC) of the numerical rating scale (NRS) score in the first 24 h after surgery and the number of parent-controlled intravenous analgesia (PCIA) boluses administered 24 h after surgery. The secondary outcomes included the NRS score, opioid consumption, rescue analgesia, adverse events, and quality of recovery.

RESULTS

The AUC-NRS at rest was 62 (13) in the ESPB group and 89 (13) in the control group (P < 0.001). There were 15 (5) 24-h PCIA boluses administered in the ESPB group and 30 (7) in the control group (P < 0.001). Compared with those in the control group, the NRS scores at rest were lower in the ESPB group at 0, 3, 6, and 9 h postoperatively, and the NRS scores during movement were lower in the ESPB group at 0, 3, 6, 9 and 12 h postoperatively. The ESPB group showed a lower need for PCIA than did the control group at 0-6, 6-12, 12-18 and 1-24 h postoperatively. In the ESPB group, fewer patients required rescue analgesics, and patients exhibited a higher quality of recovery.

CONCLUSION

Preoperative ESPB improves postoperative analgesia in paediatric scoliosis patients who underwent PSF.

TRIAL REGISTRATION NUMBER

ChiCTR2300074505.

DATE OF REGISTRATION

August 8, 2023.

摘要

目的

大脊柱手术会引起剧烈疼痛。我们研究了竖脊肌平面阻滞(ESPB)在小儿脊柱侧弯后路脊柱融合(PSF)术后缓解疼痛的能力。

方法

72 名接受 PSF 的患者随机分为术前超声引导 ESPB 组或无阻滞对照组。主要复合终点是术后 24 小时内数字评分量表(NRS)评分的曲线下面积(AUC)和术后 24 小时内给予的家长控制静脉镇痛(PCIA)推注次数。次要结果包括 NRS 评分、阿片类药物用量、解救性镇痛、不良事件和恢复质量。

结果

ESPB 组静息时 AUC-NRS 为 62(13),对照组为 89(13)(P<0.001)。ESPB 组有 15(5)次 24 小时 PCIA 推注,对照组有 30(7)次(P<0.001)。与对照组相比,ESPB 组在术后 0、3、6 和 9 小时静息时 NRS 评分较低,术后 0、3、6、9 和 12 小时运动时 NRS 评分较低。ESPB 组在术后 0-6、6-12、12-18 和 1-24 小时时需要 PCIA 的次数比对照组少。在 ESPB 组中,需要解救性镇痛的患者较少,且患者的恢复质量更高。

结论

术前 ESPB 可改善接受 PSF 的小儿脊柱侧弯患者的术后镇痛效果。

试验注册号

ChiCTR2300074505。

注册日期

2023 年 8 月 8 日。

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