De Lalla F, Rizzardini G, Angelucci B
Chemioterapia. 1987 Feb;6(1):50-1.
Two hundred and seventy-one male patients suffering from uncomplicated gonococcal urethritis were treated in an open randomized study with either 250 mg (121 patients) or 500 mg (150 patients) single oral doses of ciprofloxacin. The efficacy of treatment was verified on the third day by direct examination of urethral swabs in 91 patients and by culture and direct microscopic examination in 180 subjects. Cure rates were 100% in the 500 mg group and 96.6% in the 250 mg treated patients. No side effects were seen. Ciprofloxacin appears to be a very effective and safe drug in the treatment of uncomplicated gonococcal urethritis in men.
在一项开放性随机研究中，271例单纯性淋菌性尿道炎男性患者，分别接受250mg（121例患者）或500mg（150例患者）单次口服环丙沙星治疗。在第3天，通过对91例患者的尿道拭子直接检查以及对180例受试者进行培养和直接显微镜检查来验证治疗效果。500mg组的治愈率为100%，250mg治疗组患者的治愈率为96.6%。未观察到副作用。环丙沙星似乎是治疗男性单纯性淋菌性尿道炎非常有效且安全的药物。
