Department of Orthopedics and Tumororthopedics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.
Department of General Paediatrics, University Children's Hospital Muenster, Albert-Schweitzer-Campus 1, 48149, Muenster, Germany.
BMC Musculoskelet Disord. 2022 Apr 30;23(1):405. doi: 10.1186/s12891-022-05362-1.
The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis.
This single-center study is a retrospective review of 17 patients with primary ABCs of the pelvis. It examines the importance of polidocanol instillations as minimally invasive treatment option for ABCs of the pelvis compared to intralesional curettage or marginal resection.
Seventeen patients with the diagnosis of a primary ABC of the pelvis were included in the study. Six patients were male (35%) and 11 patients female (65%); the mean age was 18 (9-49) years. The mean follow-up time was 50 months (12-136 months). The most common location of manifestation was the pubis (6; 35%), followed by the ilium (6; 35%), the sacrum (3; 18%) and the ischium (2; 12%). Eight patients were treated by intralesional curettage with the use of adjuvants, one patient by marginal resection, seven by sequential instillation of polidocanol and one patient by simple observation. Five patients received an additional transarterial embolization. After intralesional curettage local recurrence was detected in 4/8 cases (50%). After instillation therapy six patients (86%) had a stable disease without recurrence, only one patient (14%) had a persistent disease with need of additional treatment and was therefore converted to intralesional curettage without local recurrence in the follow-up.
Sequential instillations of polidocanol are a promising, minimally invasive treatment method for ABCs of the pelvis and can be well combined with transarterial embolization.
动脉瘤样骨囊肿(ABC)是一种良性但局部侵袭性的骨囊性病变。它通常发生在青少年和年轻成年人的长骨干骺端,但也可影响骨盆。
本单中心研究回顾性分析了 17 例原发性骨盆 ABC 患者。研究考察了与病灶内刮除术或边缘切除术相比,将聚多卡醇灌注作为骨盆 ABC 的微创治疗选择的重要性。
研究纳入了 17 例原发性骨盆 ABC 患者。其中男 6 例(35%),女 11 例(65%);平均年龄 18 岁(9-49 岁)。平均随访时间为 50 个月(12-136 个月)。最常见的表现部位为耻骨(6 例,35%),其次为髂骨(6 例,35%)、骶骨(3 例,18%)和坐骨(2 例,12%)。8 例患者采用病灶内刮除术联合辅助治疗,1 例患者行边缘切除术,7 例患者行聚多卡醇序贯灌注治疗,1 例患者单纯观察。5 例患者接受了额外的经动脉栓塞治疗。病灶内刮除术后,4/8 例(50%)局部复发。灌注治疗后,6 例(86%)患者疾病稳定无复发,仅 1 例(14%)患者疾病持续存在,需要额外治疗,因此改行病灶内刮除术,随访中无局部复发。
聚多卡醇序贯灌注是一种有前途的、微创的骨盆 ABC 治疗方法,可与经动脉栓塞治疗很好地结合。