Okudan Berna, Seven Bedri, Ural Betül, Çapraz Mustafa
Department of Nuclear Medicine, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.
Department of Nuclear Medicine, Sabuncuoğlu Şerefeddin Training and Research Hospital, University of Amasya, Amasya, Turkey.
Curr Med Imaging. 2022;18(14):1532-1535. doi: 10.2174/1573405618666220427134647.
A series of pneumonia cases with clinical presentations of viral pneumonia secondary to new coronavirus and subsequent global transmission arose in Wuhan, Hubei, China, in December 2019. Several cases of coronavirus disease 2019 (COVID-19) have been described incidentally in positron emission tomography-computed tomography (PET/CT) with F-fluorodeoxyglucose (FDG) as a result of the pandemic. Herein, we describe the findings of a patient with unknown COVID-19 in PET/CT with the other radiopharmaceutical, Ga-labeled prostatespecific membrane antigen (Ga-PSMA).
A 69-year-old man had previously undergone radical prostatectomy for adenocarcinoma. Ga-PSMA PET/CT imaging was performed due to biochemical recurrence. Ga-PSMA uptake in the prostate bed suggestive of local recurrence was detected in PET/CT images. Also, bilateral groundglass opacities with slightly increased Ga-PSMA uptake were seen in the lungs, suspected of COVID-19. A reverse transcription-polymerase chain reaction test has confirmed the infection.
Even in asymptomatic patients, nuclear medicine departments must be aware of the possibility of COVID-19, take appropriate post-exposure procedures, and protect employees and other patients.
2019年12月，中国湖北武汉出现了一系列临床表现为新型冠状病毒继发病毒性肺炎并随后全球传播的肺炎病例。由于疫情大流行，在以氟脱氧葡萄糖（FDG）进行正电子发射断层扫描-计算机断层扫描（PET/CT）检查时偶然发现了几例2019冠状病毒病（COVID-19）病例。在此，我们描述了一名COVID-19情况不明的患者在使用另一种放射性药物镓标记前列腺特异性膜抗原（Ga-PSMA）进行PET/CT检查时的结果。
一名69岁男性此前因腺癌接受了根治性前列腺切除术。因生化复发进行了Ga-PSMA PET/CT成像检查。在PET/CT图像中检测到前列腺床有Ga-PSMA摄取，提示局部复发。此外，肺部可见双侧磨玻璃影，Ga-PSMA摄取略有增加，怀疑为COVID-19。逆转录聚合酶链反应检测证实了感染。
即使是无症状患者，核医学科室也必须意识到COVID-19的可能性，采取适当的暴露后程序，保护员工和其他患者。
