Brychta Ivan, Mayer Alexander, Gergel Michal, Vidiscak Marian, Plank Karol
1st Surgical Clinic, Slovak Medical University and University Hospital Bratislava, Slovakia.
1st Clinic of Gynecology and Obstetrics, Slovak Medical University and University Hospital Bratislava, Slovakia.
Neuro Endocrinol Lett. 2021 Dec 21;42(8):517-521.
Primary hyperparathyroidism (PHPT) in pregnancy is rare and may be associated with increased maternal and fetal morbidity and mortality. The ideal timing for parathyroidectomy is during the second trimester, and parathyroidectomy in the third trimester is extremely rare. We present a case of a 32-year-old woman who was admitted to our hospital with severe hypercalcemia in the 36th week of her first pregnancy. Conventional bilateral neck exploration was performed and parathyroid adenoma was removed. The surgical procedure was tolerated well by the mother, and she delivered a healthy girl 10 days after surgery. The newborn had mild hypocalcemia that required minimal substitution postnatally; however, no tetany occurred. This case demonstrates that parathyroidectomy in the third trimester followed by spontaneous delivery may be performed safely.
妊娠合并原发性甲状旁腺功能亢进症（PHPT）较为罕见，可能会增加孕产妇和胎儿的发病及死亡风险。甲状旁腺切除术的理想时机是在孕中期，而在孕晚期进行甲状旁腺切除术极为罕见。我们报告一例32岁女性病例，她在首次怀孕的第36周因严重高钙血症入住我院。进行了常规双侧颈部探查并切除了甲状旁腺腺瘤。母亲对手术耐受性良好，术后10天分娩出一名健康女婴。新生儿有轻度低钙血症，出生后仅需少量补充钙剂；然而，未发生手足搐搦。该病例表明，孕晚期进行甲状旁腺切除术后自然分娩可能是安全的。
