Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas, USA.
Department of Pediatrics, Division of Neonatology, University of Texas Medical Branch, Galveston, Texas, USA.
J Neonatal Perinatal Med. 2022;15(4):863-866. doi: 10.3233/NPM-210819.
There are multiple manifestations in the neonatal period for infants born to mothers with systematic lupus erythematosus (SLE), ranging from cardiac, hematologic and dermatologic abnormalities. Cardiac complications may arise in utero in the form of heart block with a resulting increase in fetal mortality. The fetal conduction system is suspected to be affected by transplacental maternal antibodies, however additional environmental and fetal factors appear to play a role. We describe a rare case of a dichorionic-diamniotic twin pregnancy in which only one twin developed a complete heart block progressing to hydrops fetalis and fetal demise.
患有系统性红斑狼疮（SLE）的母亲所生婴儿在新生儿期有多种表现，包括心脏、血液和皮肤异常。心脏并发症可能在宫内以心脏传导阻滞的形式出现，从而导致胎儿死亡率增加。胎儿传导系统被怀疑受胎盘母体抗体影响，但其他环境和胎儿因素似乎也起作用。我们描述了一例罕见的双绒毛膜-双羊膜双胞胎妊娠，其中只有一胎发展为完全性心脏传导阻滞，进而出现胎儿水肿和胎儿死亡。
