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镶嵌成形术的新概念:覆盖有细胞化支架的自体骨膜圆柱移植体

A New Concept of Mosaicplasty: Autologous Osteoperiosteal Cylinder Graft Covered With Cellularized Scaffold.

作者信息

Bozkurt Murat, Uysal Ozgur, Kilic Erden, Emre Fahri, Kaya Ozgur

机构信息

Department of Orthopaedics and Traumatology, School of Medicine, Ankara Yildirim Beyazit University.

Orthopaedics Clinic, Ankara Yuzuncu Yıl Hospital.

出版信息

Arthrosc Tech. 2022 Mar 28;11(4):e655-e660. doi: 10.1016/j.eats.2021.12.033. eCollection 2022 Apr.

DOI:10.1016/j.eats.2021.12.033
PMID:35493035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9052156/
Abstract

A concern regarding osteochondral autograft transfer for chondral defects is donor-site morbidity of the knee, the most common source of the autograft. To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acid-based polymer scaffold pretreated with bone marrow aspirate concentrate and transferred to the chondral defect recipient site in the exact size for restoration of the subchondral bone and the articular cartilage.

摘要

对于软骨缺损的自体骨软骨移植,一个令人担忧的问题是膝关节供区的并发症,这是自体移植物最常见的来源。为避免自体骨软骨移植的缺点,从髂嵴获取一个圆柱形骨膜骨移植物,该移植物覆盖有经骨髓抽吸浓缩物预处理的相同尺寸的基于透明质酸的聚合物支架圆柱体,并以精确尺寸转移至软骨缺损受区,用于修复软骨下骨和关节软骨。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/ddf9a65b2a10/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/15be054ba8b0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/610b92cda6de/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/96068af0d68d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/9b99a2e45bfd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/c21f2c1eae69/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/646385830d4b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/ddf9a65b2a10/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/15be054ba8b0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/610b92cda6de/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/96068af0d68d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/9b99a2e45bfd/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/c21f2c1eae69/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/646385830d4b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef7/9052156/ddf9a65b2a10/gr7.jpg

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本文引用的文献

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Matrix-Induced Autologous Chondrocyte Implantation (MACI) Grafting for Osteochondral Lesions of the Talus.基质诱导自体软骨细胞植入术(MACI)治疗距骨骨软骨病变。
Foot Ankle Int. 2020 Sep;41(9):1099-1105. doi: 10.1177/1071100720935110. Epub 2020 Jul 8.
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All-Arthroscopic Osteochondral Autograft Transfer Technique for Osteochondritis Dissecans of the Talus.
全关节镜下距骨剥脱性骨软骨炎自体骨软骨移植技术
Arthrosc Tech. 2020 Mar 13;9(4):e499-e503. doi: 10.1016/j.eats.2019.12.002. eCollection 2020 Apr.
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BMJ Open. 2020 Feb 9;10(2):e033850. doi: 10.1136/bmjopen-2019-033850.
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Arthroscopic Microfracture for Osteochondral Lesions of the Talus: Functional Outcomes at a Mean of 6.7 Years in 165 Consecutive Ankles.关节镜下微骨折术治疗距骨骨软骨病变:165 例连续踝关节平均 6.7 年的功能结果。
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