Binas B, Grosse R
FEBS Lett. 1987 Mar 9;213(1):164-8. doi: 10.1016/0014-5793(87)81484-9.
Epidermal growth factor and 12-O-tetradecanoylphorbol-13-acetate increased the amount of 32Pi found as phosphoserine in a major, hitherto not described 58 kDa phosphoprotein (pp58) secreted by normal rat kidney fibroblasts. Platelet-derived growth factor, insulin, nerve growth factor and fibroblast growth factor did not affect pp58 while transforming growth factor beta decreased the accumulation of radioactivity into pp58. Cycloheximide, actinomycin D and ammonium chloride suppressed the labelling of pp58.
表皮生长因子和12 - O - 十四烷酰佛波醇 - 13 - 乙酸盐增加了在正常大鼠肾成纤维细胞分泌的一种主要的、迄今未描述的58 kDa磷蛋白（pp58）中作为磷酸丝氨酸存在的32Pi的量。血小板衍生生长因子、胰岛素、神经生长因子和成纤维细胞生长因子对pp58没有影响，而转化生长因子β降低了pp58中放射性的积累。放线菌酮、放线菌素D和氯化铵抑制了pp58的标记。
