Gentile F, Lira O, Marcano-de Cotte D
Gen Comp Endocrinol. 1986 Nov;64(2):239-45. doi: 10.1016/0016-6480(86)90008-0.
Immunoreactive gonadotrophic hormone-releasing hormone (ir-GnRH) was detected in hypothalamic and telencephalic extracts of the Venezuelan freshwater fish "caribe colorado," Pygocentrus notatus. Hypothalamic ir-GnRH from female fish demonstrated displacement curves parallel to those of synthetic mammalian luteinizing hormone-releasing hormone (LHRH). The content of hypothalamic and telencephalic ir-GnRH from female fish was more than four-fold greater than that of male animals. Also, fluctuations that depended on the reproductive state and environmental conditions (rainfall) occurred in females but not in males. Thus, ir-GnRH levels were higher in hypothalamic and telencephalic extracts from sexually mature females than in those from fish sampled outside the climatically determined breeding season.
在委内瑞拉淡水鱼“红腹食人鱼”（Pygocentrus notatus）的下丘脑和端脑提取物中检测到了免疫反应性促性腺激素释放激素（ir-GnRH）。雌性鱼下丘脑的ir-GnRH显示出与合成的哺乳动物促黄体生成素释放激素（LHRH）平行的置换曲线。雌性鱼下丘脑和端脑ir-GnRH的含量比雄性动物高四倍多。此外，雌性鱼中出现了依赖于生殖状态和环境条件（降雨）的波动，而雄性鱼则没有。因此，性成熟雌性鱼的下丘脑和端脑提取物中的ir-GnRH水平高于在气候决定的繁殖季节之外采样的鱼。
