1α-羟基皮质酮结合蛋白在鳐鱼中的细胞定位。
The cellular location of 1 alpha-hydroxycorticosterone binding protein in skate.
作者信息
Burton M, Idler D R
出版信息
Gen Comp Endocrinol. 1986 Nov;64(2):260-6. doi: 10.1016/0016-6480(86)90012-2.
Antiserum to 1 alpha-hydroxycorticosterone binding protein was used to investigate its location in selected tissues of the skate Raja ocellata. Immunofluorescence, using an indirect technique, showed 1 alpha-hydroxycorticosterone binding sites in potential target tissue: gill. chloride cells, rectal gland parenchyma, and a portion of the kidney tubule. The binding protein was not detectable in the ventricle or the intestinal spiral valve but was associated with liver parenchyma and interrenal cells. The intracellular location of the binding protein is apparently tissue specific.
使用抗1α-羟基皮质酮结合蛋白的抗血清来研究其在眼斑鳐（Raja ocellata）特定组织中的定位。采用间接技术进行免疫荧光检测，结果显示在潜在靶组织中存在1α-羟基皮质酮结合位点，这些组织包括鳃、氯细胞、直肠腺实质以及一部分肾小管。在心室或肠螺旋瓣中未检测到该结合蛋白，但其与肝实质和肾上腺皮质细胞相关。结合蛋白在细胞内的定位显然具有组织特异性。
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