Department of Neurosurgery, Yangzhou Hongquan Hospital, Yangzhou 225200, Jiangsu, China.
J Healthc Eng. 2022 Apr 21;2022:8280540. doi: 10.1155/2022/8280540. eCollection 2022.
The incidence of pituitary adenoma is second only to glioma and meningioma, and its incidence ranks third among intracranial tumors. Most pituitary adenomas are benign and noninvasive tumors, but invasive pituitary adenomas pose a great threat to human health. In order to explore the risk factors that affect the clinical aggressive behavior of patients with pituitary adenoma, analyze the correlation between different classification methods and clinical aggressive behavior, and lay the foundation for early judgment and individualized treatment of clinical aggressive behavior of patients with pituitary adenoma. We conducted statistical research on patients who were treated for pituitary adenomas in the city's Yangzhou Hongquan Hospital. The results of the study showed that six patients in this study showed aggressiveness in the clinical symptomatic outcome, six patients showed aggressiveness in the serological outcome, and seven patients showed aggressiveness in imaging. In the multimodal classification, the clinical aggressiveness of pituitary adenomas in the invasion + atypical group was significantly higher than that in other groups, and the difference was statistically significant ( < 0.05). The correlation analysis of magnetic resonance imaging features and prognosis of invasive pituitary adenomas were verified to be feasible for the treatment of patients.
垂体腺瘤的发病率仅次于胶质瘤和脑膜瘤，其在颅内肿瘤中的发病率位居第三。大多数垂体腺瘤为良性、非侵袭性肿瘤，但侵袭性垂体腺瘤对人类健康构成了极大威胁。为了探讨影响垂体腺瘤患者临床侵袭性行为的危险因素，分析不同分类方法与临床侵袭性行为的相关性，为垂体腺瘤患者临床侵袭性行为的早期判断和个体化治疗奠定基础。我们对在我市扬州洪泉医院治疗的垂体腺瘤患者进行了统计研究。研究结果表明，在本研究中，有 6 例患者在临床症状性结局方面表现出侵袭性，6 例患者在血清学结局方面表现出侵袭性，7 例患者在影像学方面表现出侵袭性。在多模态分类中，侵袭性+非典型组的垂体腺瘤临床侵袭性明显高于其他组，差异有统计学意义（<0.05）。对侵袭性垂体腺瘤的磁共振成像特征与预后的相关性分析验证了其对患者治疗的可行性。
