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新冠病毒病住院期间慢性淋巴细胞白血病的出现:病因还是巧合?

Emergence of Chronic Lymphocytic Leukemia During Admission for COVID-19: Cause or Coincidence?

作者信息

Saluja Prachi, Gautam Nitesh, Amisha Fnu, Safar Mazin, Bartter Thaddeus

机构信息

Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.

Department of Hematology and Medical Oncology, University of Arkansas for Medical Sciences, Little Rock, USA.

出版信息

Cureus. 2022 Mar 24;14(3):e23470. doi: 10.7759/cureus.23470. eCollection 2022 Mar.

Abstract

Chronic lymphocytic leukemia (CLL) is the most common leukemia affecting the western adult population. While CLL is known to be a risk factor for morbidity and mortality from coronavirus disease 2019 (COVID-19), COVID-19 has not been shown to be a risk factor for the development of CLL. We report a case of a 55-year-old man who presented with COVID-19 pneumonia and developed overt CLL during hospitalization. Four other cases were culled from the literature. We discuss mechanistic possibilities for the unmasking of CLL in susceptible individuals with COVID-19.

摘要

慢性淋巴细胞白血病(CLL)是影响西方成年人群的最常见白血病。虽然已知CLL是2019冠状病毒病(COVID-19)发病和死亡的危险因素,但尚未证明COVID-19是CLL发生的危险因素。我们报告了一例55岁男性患者,他因COVID-19肺炎入院,并在住院期间发展为明显的CLL。另外从文献中筛选出4例病例。我们讨论了在感染COVID-19的易感个体中揭示CLL的机制可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03e6/9038577/dc36d2c582be/cureus-0014-00000023470-i01.jpg

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