Moez Rahoui, Boulma Rami, Hassen Khouni
Urology Resident, Departement of Urology, FSI Hospital La Marsa, Tunisia.
Senior Urologist Surgeon at Department of Urology, FSI Hospital La Marsa, Tunisia.
Ann Med Surg (Lond). 2022 Apr 4;76:103561. doi: 10.1016/j.amsu.2022.103561. eCollection 2022 Apr.
and importance: Urethral cancer is a rare condition. It represents less than 1% of all cancers and the clinical signs are not very specific and confusing, which explains the often-late diagnosis. The prognosis can be poor. The objective of our observation is to discuss, through a review of the literature, the diagnostic and therapeutic means of tumors of the male anterior urethra.
This is a 54-year-old patient, smoker, followed for urinary lithiasis. He initially consulted us for right nephritic colic, with an obstructive iliac ureteral stone on a CT scan. He had drainage by JJ stent followed by extracorporeal lithotripsy. After three months, it was decided to remove the JJ Stent. During urethrocystoscopy, a papillary tumor of the anterior urethra was found, measuring 0.5 cm on the long axis. Endoscopic resection of the tumor was performed. Pathological examination revealed a low-grade malignant urothelial carcinoma. No tumor recurrence was noted after one year of follow-up.
Primary urethral cancer is a rare condition. Most series in the literature show a male predominance. The main risk factors are chronic inflammation, history of urethritis, and urethral stricture. The clinical signs of urethral cancer are usually discrete and not very specific. The reference examination for positive diagnosis remains urethroscopy, which allows a more precise diagnosis thanks to a direct view of the urethral mucosa. The management of tumors of the anterior urethra consisted of aggressive excisional surgery. The main goal was to achieve satisfactory local control. conservative treatment by resection, fulguration or laser vaporization is indicated for small lesions (<1 cm).
Tumors of the anterior urethra in men are often diagnosed late. More effort should be made to diagnose this disease earlier, especially in high-risk groups. Conservative treatment can be offered in patients with a small lesion.
及重要性:尿道癌是一种罕见疾病。它在所有癌症中所占比例不到1%,临床症状不太具有特异性且容易混淆,这就导致了诊断往往较晚。其预后可能较差。我们此次观察的目的是通过文献综述,探讨男性前尿道肿瘤的诊断和治疗方法。
这是一名54岁的男性患者,有吸烟史,因尿路结石前来就诊。他最初因右侧肾绞痛前来我院,CT扫描显示髂段输尿管有梗阻性结石。先通过置入双J管引流,随后进行了体外冲击波碎石术。三个月后,决定取出双J管。在尿道膀胱镜检查时,发现前尿道有一个乳头状肿瘤,长轴为0.5厘米。对肿瘤进行了内镜切除。病理检查显示为低级别恶性尿路上皮癌。随访一年后未发现肿瘤复发。
原发性尿道癌是一种罕见疾病。文献中的大多数系列研究表明男性居多。主要危险因素包括慢性炎症、尿道炎病史和尿道狭窄。尿道癌的临床症状通常不明显且特异性不强。确诊的参考检查仍是尿道镜检查,通过直接观察尿道黏膜能做出更精确诊断。前尿道肿瘤的治疗包括积极的切除手术。主要目标是实现满意的局部控制。对于小病变(<1厘米),可采用切除、电灼或激光汽化等保守治疗方法。
男性前尿道肿瘤往往诊断较晚。应更加努力地早期诊断这种疾病,尤其是在高危人群中。对于病变较小的患者可采用保守治疗。