一例复发性骨折的神秘病例：肿瘤诱导的骨软化症。
A mysterious case of recurrent fracture: Tumour-induced osteomalacia.
作者信息
Shetty Sahana, Ravindra Shruthi, Acharya Himamshu, Rao Sharath K
机构信息
Department of Endocrinology, Kasturba Medical College, Manipal Academy of Higher Education, MAHE, Manipal, Karnataka, India.
Department of Orthopaedics, Kasturba Medical College, Manipal Academy of Higher Education, MAHE, Manipal, Karnataka, India.
出版信息
J Family Med Prim Care. 2022 Mar;11(3):1204-1207. doi: 10.4103/jfmpc.jfmpc_947_21. Epub 2022 Mar 10.
We report a case of tumour-induced osteomalacia in a 59-year-old man who presented with a long-standing history of myalgia, bone pain and pathological fracture of the bilateral femur at different intervals in the past 4 years. A biochemical evaluation revealed hypophosphatemia secondary to phosphaturia. Localization study by Ga-68 DOTANOC PET-CT for adult-onset hypophosphatemic osteomalacia revealed a tumour in the right femoral head. Resection of the tumour resulted in clinical improvement as well as normalization of biochemical parameters.
我们报告一例59岁男性的肿瘤诱导性骨软化症病例，该患者在过去4年中不同时间出现了长期的肌痛、骨痛以及双侧股骨病理性骨折病史。生化评估显示，由于磷酸盐尿导致低磷血症。通过Ga-68 DOTANOC PET-CT对成人迟发性低磷血症性骨软化症进行定位研究，发现右股骨头有一个肿瘤。切除该肿瘤后，临床症状改善，生化指标也恢复正常。
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