Gomar-Sancho F, Gastaldi Orquin E
Int Orthop. 1987;11(1):65-9. doi: 10.1007/BF00266060.
Repair of osteochondral defects in articular weightbearing areas presents its own particular problems because of the low potential of hyaline cartilage for regeneration. Our first group of experiments on the knee of the rabbit confirms that the new regenerated cartilage comes from bone marrow which degenerates before developing into true hyaline cartilage. The second group of experiments shows that autologous grafts from the non-weightbearing articular area suitable for the repair of defects in weightbearing areas. In an third group, autologous meniscal fibrocartilage was used as a graft for the repair of osteochondral defects.
由于透明软骨再生能力低,关节负重区域骨软骨缺损的修复存在其自身特殊的问题。我们在兔膝关节上进行的第一组实验证实,新再生的软骨来自骨髓,骨髓在发育成真正的透明软骨之前会退化。第二组实验表明,来自非负重关节区域的自体移植物适合修复负重区域的缺损。在第三组实验中,自体半月板纤维软骨被用作修复骨软骨缺损的移植物。