Gündüz Özgür, Koçak Gülşah, Kaçmaz Birgül, Devrim Tuba, Şimşek Hülya
Department of Dermatology, University of Kirikkale, Kirikkale, Turkey.
Department of Dermatology and Venerology, İstanbul Başakşehir Çam ve Sakura City Hospital, Istanbul, Turkey.
Case Rep Dermatol. 2022 Mar 21;14(1):49-54. doi: 10.1159/000523797. eCollection 2022 Jan-Apr.
Cutaneous involvement is a relatively uncommon manifestation of tuberculosis (TB), particularly outside the endemic regions. Cutaneous TB manifests itself in various clinical forms, depending on the host's immune status and mode of transmission. Nonetheless, the same treatment regimen is recommended for every subtype. Tuberculosis verrucosa cutis (TBVC) is a specific subgroup in which the affected persons are usually healthy adults who are vaccinated or exposed to mycobacteria during their occupational activities. These patients have the ability to launch a strong cellular immune reaction against mycobacteria. In this article, we present an elderly patient with a 4-year history of TBVC who was treated with intralesional injection of avirulent Bacillus Calmette-Guérin (BCG) and report our clinical observation on the inflammatory and healing process of the patient's lesion following the intralesional BCG injection.
皮肤受累是结核病（TB）相对不常见的表现，特别是在流行地区以外。皮肤结核根据宿主的免疫状态和传播方式以各种临床形式表现出来。尽管如此，每种亚型都推荐相同的治疗方案。疣状皮肤结核（TBVC）是一个特定的亚组，其中受影响的人通常是在职业活动中接种过疫苗或接触过分枝杆菌的健康成年人。这些患者有能力对分枝杆菌发起强烈的细胞免疫反应。在本文中，我们介绍了一名有4年疣状皮肤结核病史的老年患者，该患者接受了病灶内注射无毒卡介苗（BCG）治疗，并报告了我们对病灶内注射卡介苗后患者病变的炎症和愈合过程的临床观察。
