Yuan Mingzhen, Ma Feiyan, Chen Lulu, Chen Youxin
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, 100730, China.
Department of Ophthalmology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China.
Am J Ophthalmol Case Rep. 2022 Apr 21;26:101542. doi: 10.1016/j.ajoc.2022.101542. eCollection 2022 Jun.
To describe the characteristic findings of non-invasive multi-spectral imaging (MSI) for adult-onset foveomacular vitelliform dystrophy (AFVD).
On examination of MSI, the characteristic performances of AFVD include the nodule-like high-reflecting lesions, the line-like low-reflecting lesions in the high-reflecting lesion, and the scattered high-reflecting and low-reflecting lesions around the nodule-like lesion. MSI has an advantage over color fundus photography (CFP) and fundus autofluorescence (FAF) in finding tiny lesions, which corresponded to drusenoid structures on optical coherence tomography (OCT). MSI showed different characteristics at different stages of AFVD, which may be instructive to the pathogenesis and progression of AFVD.
MSI is a promising diagnostic and follow-up tool that will provide additional information in fundus imaging for AFVD, and the changes on MSI is partially instructive to the pathogenesis and progression of AFVD.
描述成人黄斑中心凹卵黄样营养不良（AFVD）的非侵入性多光谱成像（MSI）特征性表现。
在MSI检查中，AFVD的特征性表现包括结节样高反射病变、高反射病变内的线状低反射病变以及结节样病变周围散在的高反射和低反射病变。MSI在发现微小病变方面优于彩色眼底照相（CFP）和眼底自发荧光（FAF），这些微小病变在光学相干断层扫描（OCT）上对应于玻璃膜疣样结构。MSI在AFVD的不同阶段表现出不同特征，这可能对AFVD的发病机制和进展具有指导意义。
MSI是一种有前景的诊断和随访工具，将为AFVD的眼底成像提供额外信息，且MSI上的变化对AFVD的发病机制和进展具有部分指导意义。
