视网膜色素上皮裂孔：成人中心凹黄斑卵黄样营养不良的迟发性并发症。
Retinal pigment epithelium aperture: A late-onset complication in adult-onset foveomacular vitelliform dystrophy.
作者信息
Bansal Reema, Yangzes Sonam, Singh Ramandeep, Katoch Deeksha, Dogra Mangat R, Gupta Vishali, Gupta Amod
机构信息
Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Indian J Ophthalmol. 2018 Jan;66(1):83-88. doi: 10.4103/ijo.IJO_676_17.
PURPOSE
The purpose of the study was to report aperture of retinal pigment epithelium (RPE) as a late complication and an unreported finding during the natural course of adult-onset foveomacular vitelliform dystrophy (AFVD).
METHODS
Four diagnosed cases of AFVD followed for a period ranging from 4 to 8 years. All patients had documented records of clinical examination, fundus autofluorescence and fluorescein angiography, and spectral domain-optical coherence tomography at regular intervals.
RESULTS
Besides the known stages in the natural course of AFVD, RPE aperture was noted as an additional finding during the vitelliruptive stage of the disease. The vitelliform material was noted beneath the disrupted RPE before disappearance. Accumulation of vitelliform material continued even after the vitelliruptive stage.
CONCLUSION
RPE aperture may represent an ongoing process in the natural course of AFVD.
目的
本研究的目的是报告视网膜色素上皮（RPE）裂孔作为成人发病性黄斑中心凹玻璃体样营养不良（AFVD）自然病程中的一种晚期并发症及一项未报告的发现。
方法
对4例确诊的AFVD患者进行了4至8年的随访。所有患者均有定期的临床检查、眼底自发荧光和荧光素血管造影记录，以及光谱域光学相干断层扫描记录。
结果
除了AFVD自然病程中的已知阶段外，在疾病的玻璃体破裂期还发现了RPE裂孔这一额外发现。在玻璃体样物质消失前，可见其位于破裂的RPE下方。即使在玻璃体破裂期之后，玻璃体样物质仍持续积聚。
结论
RPE裂孔可能代表AFVD自然病程中的一个持续过程。
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