Kikukawa Yuji, Kawabata Hiroko, Hayashi Yoshihito
Department of Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma Kanazawa 920-1192 Japan
RSC Adv. 2021 Sep 27;11(50):31688-31692. doi: 10.1039/d1ra05879g. eCollection 2021 Sep 21.
The cyanosilylation was performed by using metavanadate catalysts, and measurements revealed the formation of [VO(CN)] and [VOTMS] under reaction conditions. The reaction of [VO(CN)], trimethylsilyl cyanide (TMSCN), and water afforded [VOTMS] and CN, which reacted with ketones to yield the corresponding cyanohydrin trimethylsilyl ethers over [VO(CN)]. Compound [VO(CN)] showed high catalytic performance for cyanosilylation of various carbonyl compounds. In the case of -hexanal, turnover frequency reached up to 250 s.
使用偏钒酸盐催化剂进行氰基硅烷化反应，测量结果表明在反应条件下形成了[VO(CN)]和[VOTMS]。[VO(CN)]、三甲基硅基氰化物（TMSCN）和水反应生成[VOTMS]和CN，它们与酮反应，在[VO(CN)]作用下生成相应的氰醇三甲基硅基醚。化合物[VO(CN)]对各种羰基化合物的氰基硅烷化反应表现出高催化性能。对于己醛，周转频率高达250 s⁻¹。
