Di Martino Patrick
Groupe Biofilm et Comportement Microbien aux Interfaces, Laboratoire ERRMECe Cergy Paris Université, 1 rue Descartes 95000 Neuville-sur-Oise, cedex, France.
AIMS Microbiol. 2022 Jan 6;8(1):1-4. doi: 10.3934/microbiol.2022001. eCollection 2022.
Antimicrobials are therapeutic substances used to prevent or treat infections. Disinfectants are antimicrobial agents applied to non-living surfaces. Every year, several thousand tonnes of antimicrobials and their by-products are released into the environment and in particular into the aquatic environment. This type of xenobiotic has ecological consequences in the natural environment but also in technological environments such as wastewater treatment plants and methane fermentation sewage sludge treatment plants. The constant exposure of microbial communities not only to high concentrations but also to sub-inhibitory concentrations of antibiotics is a key element in the development of antibiotic resistance in aquatic environments and in soils. The future of antimicrobials lies in the development of biosourced or bioinspired molecules. The observation and deciphering of interactions between living organisms is the key to this development.
抗菌剂是用于预防或治疗感染的治疗性物质。消毒剂是应用于无生命表面的抗菌剂。每年，数千吨抗菌剂及其副产品被释放到环境中，特别是水生环境中。这类外源性物质不仅在自然环境中，而且在诸如污水处理厂和甲烷发酵污水污泥处理厂等技术环境中都具有生态影响。微生物群落持续暴露于高浓度以及亚抑制浓度的抗生素中，是水生环境和土壤中抗生素耐药性发展的关键因素。抗菌剂的未来在于开发生物源或受生物启发的分子。观察和解读生物体之间的相互作用是这一发展的关键。
