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约旦社区药剂师对抗菌药物处方的反应:一项横断面调查。

Community Pharmacists' Responses Toward Antimicrobial Prescriptions in Jordan: A Cross-Sectional Survey.

作者信息

Al-Odat Ma'en, Mustafa Shadi, Al-Hajaya Yousef, Kandari Anwar, Alaroud Amane, Alenezi Ahmad, Qaralleh Haitham, Hazaimeh Yasmeen

机构信息

Department of Medical Laboratory Science, Faculty of Allied Medical Science, Mutah University, Karak 61710, Jordan.

Faculty of Pharmacy, Jerash University, Jerash 26150, Jordan.

出版信息

Antibiotics (Basel). 2025 Mar 14;14(3):300. doi: 10.3390/antibiotics14030300.

Abstract

Globally, community pharmacists worldwide have prescribed more over-the-counter systemic antibiotics, posing significant issues for international organizations tackling antibiotic-resistant bacteria, a major global threat, due to the accessibility in pharmacies. This study aimed to examine the Jordanian pharmacists' antibiotic selection and over-the-counter antibiotic prescriptions. A total of 244 community pharmacists participated in an online standardized survey, which examined five essential domains including sources and trust of pharmacy antibiotic prescription information, category and frequency of permitted antimicrobials, prescription-free antimicrobials, interactions, antimicrobial prescription issues for pharmacists, and pharmacy staff's knowledge of non-prescription antimicrobial questions and answers. This study found that 1-pharmacists are confident in prescribing antibiotics and they use various tools to improve their skills. 2-Antibiotics were the most sought antimicrobials without a prescription, followed by antifungals and antivirals. 3-Throat, urinary tract, chest, and otitis media are the most common infections that require antibiotics. Pharmacists prescribe penicillin for 75% of throat infections, Fluoroquinolones for 48.2% of urinary tract infections, and cephalosporins for 35.9%. Macrolides are the most prevalent otitis media treatment (43.2%). 4-Some people obtain antimicrobial prescriptions without a valid reason or diagnosis. 5-Many pharmacists (171/244, 70%) agree or strongly believe that antibiotic prescription information is difficult to obtain. 6-Many pharmacists (183/200, 91.5%) aimed to educate patients on the risks and correct use of antimicrobials without prescriptions. These results show that Jordanian community pharmacists follow clinical antibiotic prescribing guidelines and conduct antimicrobial stewardship, yet they demand antimicrobials without prescriptions and lack decision support tools. Antibiotic classes address most diseases, and pharmacists emphasize antimicrobial misuse.

摘要

在全球范围内,由于药店易于获取抗生素,世界各地的社区药剂师开出了更多的非处方全身性抗生素,这给应对抗生素耐药细菌这一重大全球威胁的国际组织带来了重大问题。本研究旨在调查约旦药剂师对抗生素的选择和非处方抗生素处方情况。共有244名社区药剂师参与了一项在线标准化调查,该调查考察了五个关键领域,包括药店抗生素处方信息的来源和可信度、允许使用的抗菌药物类别和频率、无需处方的抗菌药物、相互作用、药剂师的抗菌药物处方问题以及药店工作人员对非处方抗菌药物问答的了解情况。本研究发现:1. 药剂师对开出抗生素很有信心,并且他们使用各种工具来提高自己的技能。2. 抗生素是最常被寻求的无需处方的抗菌药物,其次是抗真菌药和抗病毒药。3. 咽喉、尿路、胸部和中耳炎是最常见的需要使用抗生素的感染。药剂师开出的治疗咽喉感染的药物中75%是青霉素,治疗尿路感染的药物中48.2%是氟喹诺酮类,治疗胸部感染的药物中35.9%是头孢菌素。大环内酯类是最常用的中耳炎治疗药物(43.2%)。4. 一些人在没有正当理由或诊断的情况下获得抗菌药物处方。5. 许多药剂师(171/244,70%)同意或坚信难以获取抗生素处方信息。6. 许多药剂师(183/200,91.5%)旨在对患者进行关于无处方使用抗菌药物的风险和正确用法的教育。这些结果表明,约旦社区药剂师遵循临床抗生素处方指南并开展抗菌药物管理工作,但他们在无处方情况下仍有对抗菌药物的需求,并且缺乏决策支持工具。抗生素类别可应对大多数疾病,药剂师强调抗菌药物的滥用问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d5f/11939746/a19120b3b319/antibiotics-14-00300-g001.jpg

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