Glasgow R E, McCaul K D, Schafer L C
J Chronic Dis. 1987;40(5):399-412. doi: 10.1016/0021-9681(87)90173-1.
This study investigated the degree of adherence to different aspects of the diabetic treatment regimen (insulin injections, glucose testing, diet, and exercise), the consistency of adherence across different regimen areas, and relationships between adherence and glycemic control. A predominantly adult community sample of 93 insulin dependent outpatients participated in the prospective study that involved two series of home interviews separated by a 6-month interval. Multiple measures of adherence (e.g. self-report, interview/recall, self-monitoring, and objective indices) were collected for each regimen area. Results indicated that the degree of adherence was higher for medication taking and glucose testing than for regimen tasks requiring greater lifestyle modifications such as diet and exercise; there were few strong relationships between subjects' adherence to one area of the regimen and the extent to which they adhered to other regimen tasks; and no clear relationship between adherence and glycemic control could be demonstrated through either bivariate or multivariate analyses. It is recommended that regimen adherence be considered in the context of other factors that may influence glycemic control (e.g. stress, individual metabolic factors, appropriateness of regimen prescriptions) rather than assuming a one-to-one relationship between adherence and control.
本研究调查了糖尿病治疗方案不同方面(胰岛素注射、血糖检测、饮食和运动)的依从程度、不同方案领域依从性的一致性,以及依从性与血糖控制之间的关系。一个以成年人为主的93名胰岛素依赖型门诊患者的社区样本参与了这项前瞻性研究,该研究包括两轮家庭访谈,间隔6个月。针对每个方案领域收集了多种依从性测量方法(如自我报告、访谈/回忆、自我监测和客观指标)。结果表明,服药和血糖检测的依从程度高于饮食和运动等需要更大生活方式改变的方案任务;受试者在方案一个领域的依从性与他们在其他方案任务上的依从程度之间几乎没有紧密关系;通过双变量或多变量分析均未发现依从性与血糖控制之间存在明确关系。建议在可能影响血糖控制的其他因素(如压力、个体代谢因素、方案处方的适宜性)的背景下考虑方案依从性,而不是假定依从性与控制之间存在一对一的关系。