Urichuk Matthew, Easwar Vijayalakshmi, Scollie Susan, Purcell David
School of Communication Sciences and Disorders, Western University, London, Ontario, Canada.
National Centre for Audiology, Western University, London, Ontario, Canada.
Ear Hear. 2022;43(6):1669-1677. doi: 10.1097/AUD.0000000000001232. Epub 2022 May 2.
To assess the sensitivity of statistical indicators used for the objective detection of speech-evoked envelope following responses (EFRs) in infants and adults.
Twenty-three adults and 21 infants with normal hearing participated in this study. A modified/susa∫i/speech token was presented at 65 dB SPL monoaurally. Presentation level in infants was corrected using in-ear measurements. EFRs were recorded between high forehead and ipsilateral mastoid. Statistical post-processing was completed using F -test, Magnitude-Square Coherence, Rayleigh test, Rayleigh-Moore test, and Hotelling's T 2 test. Logistic regression models assessed the sensitivity of each statistical indicator in both infants and adults as a function of testing duration.
The Rayleigh-Moore and Rayleigh tests were the most sensitive statistical indicators for speech-evoked EFR detection in infants. Comparatively, Magnitude-Square Coherence and Hotelling's T 2 also provide clinical benefit for infants in all conditions after ~30 minutes of testing, whereas the F -test failed to detect responses to EFRs elicited by vowels with accuracy greater than chance. In contrast, the F-test was the most sensitive for vowel-elicited response detection for adults in short tests (<10 minute) and performed comparatively with the Rayleigh-Moore and Rayleigh test during longer test durations. Decreased sensitivity was observed in infants relative to adults across all testing durations and statistical indicators, but the effects were largest in low frequency stimuli and seemed to be mostly, but not wholly, caused by differences in response amplitude.
The choice of statistical indicator significantly impacts the sensitivity of speech-evoked EFR detection. In both groups and for all stimuli, the Rayleigh test and Rayleigh-Moore tests have high sensitivity. Differences in EFR detection are present between infants and adults regardless of statistical indicator; however, these effects are largest for low-frequency EFR stimuli and for amplitude-based statistical indicators.
评估用于客观检测婴儿和成人言语诱发包络跟随反应（EFRs）的统计指标的敏感性。
23名听力正常的成人和21名婴儿参与了本研究。以65 dB SPL的单耳声压级呈现一个经过修改的/susa∫i/语音样本。婴儿的呈现水平通过耳内测量进行校正。在高额和同侧乳突之间记录EFRs。使用F检验、幅度平方相干性、瑞利检验、瑞利 - 摩尔检验和霍特林T²检验完成统计后处理。逻辑回归模型评估了每个统计指标在婴儿和成人中作为测试持续时间函数的敏感性。
瑞利 - 摩尔检验和瑞利检验是婴儿言语诱发EFR检测中最敏感的统计指标。相比之下，幅度平方相干性和霍特林T²在测试约30分钟后的所有情况下也为婴儿提供了临床益处，而F检验未能以高于随机概率的准确度检测到元音诱发的EFR反应。相反，在短时间测试（<10分钟）中，F检验对成人元音诱发反应检测最敏感，在较长测试持续时间内与瑞利 - 摩尔检验和瑞利检验表现相当。在所有测试持续时间和统计指标中，婴儿相对于成人的敏感性均降低，但在低频刺激中影响最大，并且似乎主要但并非完全由反应幅度差异引起。
统计指标的选择显著影响言语诱发EFR检测的敏感性。在两组和所有刺激中，瑞利检验和瑞利 - 摩尔检验具有高敏感性。无论统计指标如何，婴儿和成人在EFR检测方面都存在差异；然而，这些影响在低频EFR刺激和基于幅度的统计指标中最为明显。
