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妊娠前后的身体活动与产妇心理健康:观察性研究的系统评价和荟萃分析。

Physical activity before and during pregnancy and maternal mental health: A systematic review and meta-analysis of observational studies.

机构信息

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian, China.

Program for Pregnancy and Postpartum Health, Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.

出版信息

J Affect Disord. 2022 Jul 15;309:393-403. doi: 10.1016/j.jad.2022.04.143. Epub 2022 Apr 29.

DOI:10.1016/j.jad.2022.04.143
PMID:35500685
Abstract

OBJECTIVE

To examine the influence of physical activity before and during pregnancy on maternal mental health outcomes.

METHODS

Ten electronic databases were searched up to May 11, 2021. Studies of all observational designs (except case studies and reviews) were included, which contained information on the relevant population (women before and or during pregnancy), exposures (objective or subjective measures of physical activity), comparator (low or no physical activity), and outcomes (diagnosis and symptom severity of depression or anxiety, quality of life scores, stress and emotions).

RESULTS

Forty-four observational studies (N = 132,399) were included. 'Low' to 'very low' certainty evidence revealed that compared with low levels of PA during pregnancy, high levels of PA were associated with a reduced odds of developing prenatal depression (odds ratio (OR): 0.68, 95% confidence interval (CI): 0.58 to 0.80) and anxiety (OR: 0.67, 95% CI: 0.54 to 0.83). We also found a reduction in the severity of prenatal depressive symptoms (standardized mean difference (SMD): -0.37, 95% CI -0.57 to -0.17), prenatal anxiety symptoms (SMD: -0.45, 95% CI -0.64 to -0.27), and prenatal stress (SMD: -0.33, 95% CI -0.55 to -0.11), concurrent with improved quality of life (SMD: 0.38, 95% CI 0.23 to 0.54). PA before pregnancy did not impact the outcomes of interest.

CONCLUSION

Physical activity during pregnancy is associated with a reduction in the odds and severity of prenatal depression and anxiety, as well as reduced stress and improved quality of life. PROSPERO registration number: CRD42020208469.

摘要

目的

探讨妊娠前后体力活动对产妇心理健康结局的影响。

方法

检索了截至 2021 年 5 月 11 日的 10 个电子数据库。纳入所有观察性设计的研究(除病例研究和综述外),这些研究包含了相关人群(妊娠前和/或妊娠期间的女性)、暴露(体力活动的客观或主观测量)、对照(低水平或无体力活动)和结局(抑郁或焦虑的诊断和症状严重程度、生活质量评分、压力和情绪)的信息。

结果

共纳入 44 项观察性研究(N=132399)。“低”到“非常低”确定性证据表明,与妊娠期间低水平的 PA 相比,高水平的 PA 与降低产前抑郁(比值比(OR):0.68,95%置信区间(CI):0.58 至 0.80)和焦虑(OR:0.67,95% CI:0.54 至 0.83)的发病风险相关。我们还发现,产前抑郁症状严重程度(标准化均数差(SMD):-0.37,95%CI:-0.57 至-0.17)、产前焦虑症状(SMD:-0.45,95%CI:-0.64 至-0.27)和产前压力(SMD:-0.33,95%CI:-0.55 至-0.11)均降低,同时生活质量提高(SMD:0.38,95%CI:0.23 至 0.54)。妊娠前的 PA 对这些感兴趣的结局没有影响。

结论

妊娠期间的体力活动与降低产前抑郁和焦虑的几率和严重程度以及降低压力和提高生活质量有关。PROSPERO 注册号:CRD42020208469。

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