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腹腔镜胰腺切除术术后并发症和再入院的预测因素:105 例连续病例的队列研究。一项回顾性研究。

Predictors of postoperative complications and readmissions in laparoscopic pancreas resection: Results of a cohort 105 consecutive cases. A retrospective study.

机构信息

Department of General Surgery, Clínica Universidad de Navarra, School of Medicine, University of Navarra, Pamplona, Spain.

Department of General Surgery, University and Polytechnic La Fe Hospital, Valencia, Spain.

出版信息

Cir Esp (Engl Ed). 2023 May;101(5):333-340. doi: 10.1016/j.cireng.2022.04.015. Epub 2022 Apr 29.

DOI:10.1016/j.cireng.2022.04.015
PMID:35500758
Abstract

INTRODUCTION

Laparoscopic resection of the pancreas (LRP) has been implemented to a varying degree because it is technically demanding and requires a long learning curve. In the present study we analyze the risk factors for complications and hospital readmissions in a single center study of 105 consecutive LRPs.

METHODS

We conducted a retrospective study using a prospective database. Data were collected on age, gender, BMI, ASA score, type of surgery, histologic type, operative time, hospital stay, postoperative complications, degree of severity and hospital readmission.

RESULTS

The cohort included 105 patients, 63 females and 42 males with a median age and BMI of 58 (53-70) and 25.5 (22,2-27.9) respectively. Eighteen (17%) central pancreatectomies, 5 (4.8%) enucleations, 81 (77.6%) distal pancreatectomies and one total pancreatectomy were performed. Fifty-six patients (53.3%) experienced some type of complication, of which 13 (12.3%) were severe (Clavien-Dindo > IIIb) and 11 (10.5%) patients were readmitted in the first 30 days after surgery. In the univariate analysis, age, male gender, ASA score, central pancreatectomy and operative time were significantly associated with the development of complications (P <0.05). In the multivariate analysis, male gender (OR 7.97; 95% CI 1.08-58.88)), severe complications (OR 59.40; 95% CI, 7.69-458.99), and the development of intrabdominal collections (OR 8.97; 95% CI, 1.28-63.02)) were associated with hospital readmission.

CONCLUSIONS

Age, male gender, ASA score, operative time and central pancreatectomy are associated with a higher incidence of complications. Male gender, severe complications and intraabdominal collections are associated with more hospital readmissions.

摘要

简介

腹腔镜胰腺切除术(LRP)已经在一定程度上得到实施,因为它技术要求高,需要很长的学习曲线。在本研究中,我们在一个 105 例连续 LRP 的单中心研究中分析了并发症和医院再入院的危险因素。

方法

我们使用前瞻性数据库进行了回顾性研究。收集的数据包括年龄、性别、BMI、ASA 评分、手术类型、组织学类型、手术时间、住院时间、术后并发症、严重程度和医院再入院。

结果

该队列包括 105 例患者,63 例女性和 42 例男性,中位年龄和 BMI 分别为 58(53-70)和 25.5(22,2-27.9)。18 例(17%)进行了中央胰腺切除术,5 例(4.8%)进行了胰腺肿瘤切除术,81 例(77.6%)进行了胰尾部切除术,1 例进行了全胰腺切除术。56 例(53.3%)患者出现了某种类型的并发症,其中 13 例(12.3%)为严重并发症(Clavien-Dindo > IIIb),11 例(10.5%)患者在术后 30 天内再次入院。在单因素分析中,年龄、男性、ASA 评分、中央胰腺切除术和手术时间与并发症的发生显著相关(P <0.05)。在多因素分析中,男性(OR 7.97;95% CI 1.08-58.88)、严重并发症(OR 59.40;95% CI,7.69-458.99)和腹腔内积液的发生(OR 8.97;95% CI,1.28-63.02)与医院再入院相关。

结论

年龄、性别、ASA 评分、手术时间和中央胰腺切除术与更高的并发症发生率相关。男性、严重并发症和腹腔内积液与更多的医院再入院相关。

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