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肾移植受者术前即刻菌尿伴脓尿的意义。

Significance of immediate preoperative bacteriuria with pyuria in renal transplant recipients.

作者信息

Hatch D A, Barry J M

出版信息

J Urol. 1987 Apr;137(4):633-5. doi: 10.1016/s0022-5347(17)44160-7.

DOI:10.1016/s0022-5347(17)44160-7
PMID:3550145
Abstract

The presence of bacteriuria and pyuria on urinalysis immediately before renal transplantation has resulted in cancellation of surgery because of concern about post-transplant wound infection. Of 113 renal transplant recipients reviewed 41 (36 per cent) had 5 or more white blood cells per high power field with bacteria in either a voided urine or bladder washout specimen obtained just before grafting. Of those 41 patients 2 suffered postoperative wound infections. Of 72 patients (64 per cent) with less than 5 white blood cells or no bacteria on a preoperative specimen 1 suffered a wound infection (p not significant by Fisher's exact test). Preoperative urine cultures and operative bladder cultures of all 3 patients failed to yield the organisms found later in the wound infections. The factors of sex, insulin-dependent diabetes, delayed graft function, living related versus cadaver donor and pre-transplant splenectomy had no significant relationship to wound infection rates. Renal transplantation can be performed safely in patients who have pyuria and bacteriuria but no signs or symptoms of infection.

摘要

肾移植手术前尿液分析发现菌尿和脓尿,由于担心移植后伤口感染,手术被取消。在回顾的113例肾移植受者中,41例(36%)在移植前采集的晨尿或膀胱冲洗标本中,每高倍视野有5个或更多白细胞且伴有细菌。在这41例患者中,2例发生了术后伤口感染。术前标本中白细胞少于5个或无细菌的72例患者(64%)中,1例发生了伤口感染(Fisher精确检验显示P值无显著性差异)。所有3例患者的术前尿培养和术中膀胱培养均未检出后来在伤口感染中发现的微生物。性别、胰岛素依赖型糖尿病、移植肾功能延迟、活体亲属供体与尸体供体以及移植前脾切除术等因素与伤口感染率无显著关系。对于有脓尿和菌尿但无感染体征或症状的患者,可以安全地进行肾移植。

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