Department of Pediatrics, Children's Hospital of New Orleans, New Orleans, Louisiana, USA.
Department of Pediatrics, Tulane University, New Orleans, Louisiana, USA.
Pediatr Pulmonol. 2022 Jul;57(7):1590-1599. doi: 10.1002/ppul.25948. Epub 2022 May 27.
People with cystic fibrosis (CF) have an amazing outlook with the treatment availability of highly effective modulators. Unfortunately, not all people with CF are eligible for modulators leading to continued pulmonary exacerbations and advanced lung disease. Additionally, optimizing diagnosis and evaluation for CF in the newborn period continues to be an area of focus for research. This review article will work to cover articles published in 2021 with high clinical relevance related to the above topics; however, due to the extensive body of research published, this review will not be comprehensive.
患有囊性纤维化 (CF) 的人在治疗上有了令人惊叹的进展,因为有了高效调节剂的应用。不幸的是,并非所有 CF 患者都有资格使用调节剂,这导致他们持续发生肺部恶化和进展性肺病。此外,在新生儿期优化 CF 的诊断和评估仍然是研究的重点领域。本文将综述 2021 年发表的与上述主题高度相关的临床相关文章;然而,由于发表的研究文献数量庞大,本文无法面面俱到。