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甲状旁腺功能亢进和脑钙化:病例报告。

Hyperparathyroidism and cerebral calcifications:a case report.

机构信息

Department of Neurology, People's Hospital of Wuzhou, Wuzhou, Guangxi, China.

Wuzhou Hospital of Youjiang Medical University for Nationalities, Baise, Wuzhou, Guangxi, China.

出版信息

Neurocase. 2022 Apr;28(2):226-230. doi: 10.1080/13554794.2022.2071627. Epub 2022 May 3.

Abstract

The evidence of hyperparathyroidism associated with cerebral calcifications is rare. We report a case with primary hyperparathyroidism (PHPT) and cerebral calcifications. A 63-year-old female patient with a history of hypertension presented to the neurology department due to bradykinesia and declining memory for one year.   Cranial CT and magnetic resonance imaging (MRI) scan revealed symmetrical calcifications in the basal ganglia, dentate nucleus of the cerebellum and in the gray and white matter junction. In the literature review, a total of 6 patients with PHPT had cerebral calcifications. Parathyroidectomy may provide a significant remission of cerebral calcifications in a patient with PHPT.

摘要

甲状旁腺功能亢进症相关脑钙化的证据很少见。我们报告了一例原发性甲状旁腺功能亢进症(PHPT)合并脑钙化的病例。一名 63 岁女性患者,有高血压病史,因一年来运动迟缓伴记忆力下降到神经内科就诊。头颅 CT 和磁共振成像(MRI)扫描显示基底节、小脑齿状核和灰白质交界处对称性钙化。在文献复习中,共有 6 例 PHPT 患者出现脑钙化。甲状旁腺切除术可能使 PHPT 患者的脑钙化显著缓解。

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