Rogers L F, Goldstein H M
Gastrointest Radiol. 1977 Dec 20;2(3):281-91. doi: 10.1007/BF02256506.
Radiation injury of the gastrointestinal tract requires a minimum dose of 4200 to 4500 rads. The symptoms and signs of radiation injury usually appear within 6 to 24 months following therapy. The radiation induced changes include mucosal atrophy and ulceration associated with an obliterative endarteritis in the supportive vasculo-connective tissue. The roentgen manifestations are those of an ischemic process but may also mimic those of recurrent malignant disease. Obstruction, hemorrhage, and fistula formation are common complications. Surgery is frequently required. The morbidity and mortality is considerable.
胃肠道辐射损伤需要至少4200至4500拉德的剂量。辐射损伤的症状和体征通常在治疗后6至24个月内出现。辐射引起的变化包括黏膜萎缩和溃疡,伴有支持性血管结缔组织中的闭塞性动脉内膜炎。X线表现为缺血性病变,但也可能类似复发性恶性疾病的表现。梗阻、出血和瘘管形成是常见并发症。通常需要手术治疗。发病率和死亡率都相当高。