[Importance of anthracyclines in tumors of the ovary and endometrium and soft tissue sarcomas].

Anthracyclines, especially Adriamycin stand as a major progress in cancer chemotherapy: in ovarian carcinoma anthracyclines are combined to cyclophosphamide and cisplatin to obtain a rapid and complete remission; in endometrial carcinoma Adriamycin is the most active drug for palliative treatment; in soft-tissue sarcomas, anthracyclines in combination with other drugs give 15 to 65% response rates (8 months of median duration) in metastatic situation; except in one study (NCl), all adjuvant studies with these drugs are actually negative.