PhD. Professor, Centro Universitário Integrado, Campo Mourão (PR), Brazil.
PhD. Professor, Biological and Health Sciences Division, Universidade Estadual de Ponta Grossa (UEPG), Ponta Grossa (PR), Brazil.
Sao Paulo Med J. 2022 May-Jun;140(3):398-405. doi: 10.1590/1516-3180.2021.0117.R1.14092021.
The high number of patients with end-stage kidney disease (ESRD) on hemodialysis makes it necessary to conduct studies aimed at improving their quality of life.
To evaluate brain compliance, using the Brain4care method for intracranial pressure (ICP) monitoring, among patients with ESRD before and at the end of the hemodialysis session, and to correlate ICP with the dialysis quality index (Kt/V).
Cross-sectional study conducted at a renal replacement therapy center in Brazil.
Sixty volunteers who were undergoing hemodialysis three times a week were included in this study. Brain compliance was assessed before and after hemodialysis using the noninvasive Brain4care method and intracranial pressure wave morphology was analyzed.
Among these 60 ESRD volunteers, 17 (28%) presented altered brain compliance before hemodialysis. After hemodialysis, 12 (20%) exhibited normalization of brain compliance. Moreover, 10 (83%) of the 12 patients whose post-dialysis brain compliance became normalized were seen to present good-quality dialysis, as confirmed by Kt/V > 1.2.
It can be suggested that changes to cerebral compliance in individuals with ESRD occur frequently and that a good-quality hemodialysis session (Kt/V > 1.2) may be effective for normalizing the patient's cerebral compliance.
接受血液透析的终末期肾病（ESRD）患者人数众多，因此有必要开展研究以提高他们的生活质量。
使用 Brain4care 方法监测颅内压（ICP），评估 ESRD 患者在血液透析前后的脑顺应性，并将 ICP 与透析质量指数（Kt/V）相关联。
巴西一家肾脏替代治疗中心进行的横断面研究。
本研究纳入了 60 名每周接受 3 次血液透析的志愿者。使用非侵入性的 Brain4care 方法评估血液透析前后的脑顺应性，并分析颅内压波形态。
在这 60 名 ESRD 志愿者中，有 17 名（28%）在血液透析前表现出脑顺应性改变。血液透析后，有 12 名（20%）脑顺应性恢复正常。此外，12 名患者中有 10 名（83%）在血液透析后脑顺应性恢复正常，这 10 名患者的 Kt/V > 1.2，提示他们接受了高质量的透析。
ESRD 患者的脑顺应性改变较为常见，Kt/V > 1.2 的高质量血液透析可能有助于恢复患者的脑顺应性。
