Department of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan.
Department of Cardiology, The Jikei University School of Medicine, Tokyo, Japan.
Neuropsychopharmacol Rep. 2022 Sep;42(3):256-262. doi: 10.1002/npr2.12254. Epub 2022 May 4.
Suicide attempts are an important severe psychiatric symptom and a clear outcome for mental disorders. Although the relationship between the early repolarization pattern in electrocardiogram and psychiatric disorders has recently been reported, these reports have not been able to exclude the influence of psychiatric drugs. This study aimed to investigate the relationship between the early repolarization pattern and a history of suicide attempts among patients not receiving psychiatric medication.
A total of 71 patients with a history of suicide attempts were investigated, 38 of whom were analyzed for this study. We compared the frequency of the early repolarization pattern between a suicide attempt group and a control group. Then, we investigated the association between the early repolarization pattern and the suicide attempt group by logistic regression analysis, including electrocardiographic findings associated with psychiatric disorders.
The findings indicated that the frequency of the early repolarization pattern was significantly higher in the suicide attempt group (n = 20; 52.6%) than in the control group (n = 4; 10.5%) (P < 0.001), and the results of the logistic regression analysis indicated that the early repolarization pattern was associated with suicide attempts.
These findings suggest that the early repolarization pattern is associated with a history of suicide attempts.
自杀企图是一种重要的严重精神症状，也是精神障碍的明确结果。尽管最近有报道称心电图中的早期复极模式与精神障碍之间存在关系，但这些报告未能排除精神药物的影响。本研究旨在调查未服用精神药物的患者中早期复极模式与自杀企图史之间的关系。
共调查了 71 例有自杀企图史的患者，其中 38 例进行了分析。我们比较了自杀企图组和对照组中早期复极模式的频率。然后，我们通过逻辑回归分析调查了早期复极模式与自杀企图组之间的关联，包括与精神障碍相关的心电图发现。
研究结果表明，自杀企图组（n=20；52.6%）中早期复极模式的频率明显高于对照组（n=4；10.5%）（P<0.001），逻辑回归分析结果表明早期复极模式与自杀企图有关。
这些发现表明早期复极模式与自杀企图史有关。
