Alqahtani Amal
College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, 31541, Saudi Arabia.
Department of Basic Sciences, Deanship of Preparatory Year and Supporting Studies, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 34212, Saudi Arabia.
Evid Based Complement Alternat Med. 2022 Apr 25;2022:6201067. doi: 10.1155/2022/6201067. eCollection 2022.
Spectacular developments in molecular and cellular biology have led to important discoveries in cancer research. Despite cancer is one of the major causes of morbidity and mortality globally, diabetes is one of the most leading sources of group of disorders. Artificial intelligence (AI) has been considered the fourth industrial revolution machine. The most major hurdles in drug discovery and development are the time and expenditures required to sustain the drug research pipeline. Large amounts of data can be explored and generated by AI, which can then be converted into useful knowledge. Because of this, the world's largest drug companies have already begun to use AI in their drug development research. In the present era, AI has a huge amount of potential for the rapid discovery and development of new anticancer drugs. Clinical studies, electronic medical records, high-resolution medical imaging, and genomic assessments are just a few of the tools that could aid drug development. Large data sets are available to researchers in the pharmaceutical and medical fields, which can be analyzed by advanced AI systems. This review looked at how computational biology and AI technologies may be utilized in cancer precision drug development by combining knowledge of cancer medicines, drug resistance, and structural biology. This review also highlighted a realistic assessment of the potential for AI in understanding and managing diabetes.
分子和细胞生物学的惊人发展在癌症研究中带来了重要发现。尽管癌症是全球发病和死亡的主要原因之一,但糖尿病是最主要的一组疾病来源之一。人工智能(AI)被认为是第四次工业革命的机器。药物发现和开发中最主要的障碍是维持药物研究流程所需的时间和费用。人工智能可以探索和生成大量数据,然后将其转化为有用的知识。正因为如此,全球最大的制药公司已经开始在药物开发研究中使用人工智能。在当今时代,人工智能在快速发现和开发新型抗癌药物方面具有巨大潜力。临床研究、电子病历、高分辨率医学成像和基因组评估只是有助于药物开发的几种工具。制药和医学领域的研究人员可以获取大量数据集,这些数据集可以由先进的人工智能系统进行分析。本综述探讨了如何通过结合癌症药物知识、耐药性和结构生物学,将计算生物学和人工智能技术应用于癌症精准药物开发。本综述还强调了对人工智能在理解和管理糖尿病方面潜力的现实评估。