Fujimoto Takeru, Sakamoto Hiromasa, Sakurai Takaki, Kanai Kasumi, Imai Kazuto, Aoyama Teruyoshi
Departments of Departments of Urology Kansai Electric Power Hospital Osaka Japan.
Department of Diagnostic Pathology Kansai Electric Power Hospital Osaka Japan.
IJU Case Rep. 2022 Feb 2;5(3):141-144. doi: 10.1002/iju5.12414. eCollection 2022 May.
In cases of ileal neobladder following radical cystectomy for the treatment of bladder cancer, tumor development in the isolated gut segment is extremely rare. Herein, we report a case of squamous cell and urothelial carcinomas in the ileal neobladder 23 years after radical cystectomy.
A 71-year-old man was referred to our hospital for further examination of a solitary tumor in an ileal neobladder. At the age of 48 years, he underwent radical cystectomy with ileal neobladder reconstruction. Transurethral resection of the bladder tumor was performed, and histopathological findings showed squamous cell carcinoma with high-grade urothelial carcinoma.
To our knowledge, this is the first report of squamous cell and urothelial carcinomas in an ileal neobladder. While secondary tumor development in an ileal neobladder is rare, it is a cause for concern as a late postoperative adverse event. Therefore, long-term follow-ups are recommended.
在因膀胱癌行根治性膀胱切除术后行回肠新膀胱术的病例中，孤立肠段发生肿瘤极为罕见。在此，我们报告一例在根治性膀胱切除术后23年的回肠新膀胱中发生鳞状细胞癌和尿路上皮癌的病例。
一名71岁男性因回肠新膀胱中的孤立肿瘤被转诊至我院进一步检查。48岁时，他接受了根治性膀胱切除术并进行回肠新膀胱重建。行经尿道膀胱肿瘤切除术，组织病理学检查结果显示为鳞状细胞癌合并高级别尿路上皮癌。
据我们所知，这是首例关于回肠新膀胱中鳞状细胞癌和尿路上皮癌的报告。虽然回肠新膀胱中继发性肿瘤的发生很少见，但作为术后晚期不良事件，这是一个值得关注的问题。因此，建议进行长期随访。
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