Douedi Steven, Pilarz Lauren, Al Kallas Hala, Pannu Viraaj S, Odak Mihir, Kozlik Ann, Elmedani Sarah, Elkherpitawy Islam, Campbell Natasha
Internal Medicine, Jersey Shore University Medical Center, Neptune City, USA.
Internal Medicine, St. George's University School of Medicine, True Blue, GRD.
Cureus. 2022 Mar 30;14(3):e23641. doi: 10.7759/cureus.23641. eCollection 2022 Mar.
Neuromyelitis optica spectrum disorder (NMOSD) is defined as a rare central nervous system, demyelinating, autoimmune disorder with autoantibodies against aquaporin-4. Commonly affecting females, NMOSD is known to also be a relapsing disease and can increase in severity during each episode. Diagnostic criteria include ruling out multiple sclerosis, spinal magnetic resonance imaging, and autoantibody detection. While management focuses on relapse treatment and prevention, high-dose steroids and plasma exchange have proven to be useful options. We present a case of a young female presenting with NMOSD relapse appropriately managed with plasma exchange.
视神经脊髓炎谱系障碍（NMOSD）被定义为一种罕见的中枢神经系统脱髓鞘自身免疫性疾病，伴有针对水通道蛋白4的自身抗体。NMOSD通常影响女性，已知也是一种复发性疾病，每次发作时病情会加重。诊断标准包括排除多发性硬化症、脊髓磁共振成像和自身抗体检测。虽然治疗重点是复发的治疗和预防，但大剂量类固醇和血浆置换已被证明是有效的选择。我们报告一例年轻女性NMOSD复发患者，经血浆置换得到妥善治疗的病例。
