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非肿瘤性宫颈细胞学

Nonneoplastic Cervical Cytology.

作者信息

Kamal Meherbano, Topiwala Fatema

机构信息

Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

出版信息

Cytojournal. 2022 Mar 29;19:25. doi: 10.25259/CMAS_03_06_2021. eCollection 2022.

DOI:10.25259/CMAS_03_06_2021
PMID:35510107
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9063585/
Abstract

Diagnostic cytology of cervix can be made strong if normal cytology is known thoroughly. Cervical lining comprises three layers of squamous cells, the basal, intermediate, and superficial cells. Knowing the dimensions of these cells, especially the intermediate cells, helps to diagnose the squamous intraepithelial lesions accurately. Furthermore, recognizing the parabasal cells in the menopausal smears, either singly or as syncytial aggregates, is important to avoid overdiagnosis of squamous intraepithelial lesions. The other cell type in the cervical lining is the endocervical glandular epithelium. Exfoliated endocervical cells may at times resemble endometrial glandular cells. The morphology and differences between these two cell types have been highlighted. It is essential to recognize and report endometrial cells in women of 40 years and above according to the recent Bethesda System for Reporting Cervical Cytology. The squamous epithelium of cervix and vagina is highly sensitive to estrogen and progesterone hormones. Hence, the Pap smears, if desired, can help in evaluating the hormonal status of the woman. The ratio of parabasal, intermediate, and superficial squamous cells can help in calculating various maturation indices.

摘要

如果对正常细胞学有透彻的了解，宫颈诊断性细胞学就能得到加强。宫颈内膜由三层鳞状细胞组成，即基底细胞、中层细胞和表层细胞。了解这些细胞的大小，尤其是中层细胞的大小，有助于准确诊断鳞状上皮内病变。此外，在绝经后涂片标本中识别单个或呈合体聚集的副基底细胞，对于避免鳞状上皮内病变的过度诊断很重要。宫颈内膜的另一种细胞类型是宫颈管腺上皮。脱落的宫颈管细胞有时可能类似于子宫内膜腺细胞。这两种细胞类型的形态及差异已得到强调。根据最新的《贝塞斯达宫颈细胞学报告系统》，识别并报告40岁及以上女性的子宫内膜细胞至关重要。宫颈和阴道的鳞状上皮对雌激素和孕激素高度敏感。因此，如果需要，巴氏涂片有助于评估女性的激素状态。副基底、中层和表层鳞状细胞的比例有助于计算各种成熟指数。

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