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A phase IV, multicentre, open-label study of emicizumab prophylaxis in people with haemophilia A with or without FVIII inhibitors undergoing minor surgical procedures.

作者信息

Escobar Miguel, Dunn Amy, Quon Doris, Trzaskoma Ben, Lee Lucy, Ko Richard H, Carpenter Shannon L

机构信息

University of Texas Health Science Center, Houston, Texas, USA.

Nationwide Children's Hospital, Columbus, Ohio, USA.

出版信息

Haemophilia. 2022 Jul;28(4):e105-e108. doi: 10.1111/hae.14574. Epub 2022 May 5.

DOI:10.1111/hae.14574
PMID:35510949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9544354/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a4/9544354/c4cdf4abe248/HAE-28-e105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a4/9544354/c4cdf4abe248/HAE-28-e105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46a4/9544354/c4cdf4abe248/HAE-28-e105-g001.jpg

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本文引用的文献

1
Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies.HAVEN 1-4 研究中依库珠单抗预防伴或不伴 FVIII 抑制剂的血友病 A 的长期疗效。
Blood. 2021 Apr 22;137(16):2231-2242. doi: 10.1182/blood.2020009217.
2
Management of people with haemophilia A undergoing surgery while receiving emicizumab prophylaxis: Real-world experience from a large comprehensive treatment centre in the US.接受emicizumab预防治疗的 A 型血友病患者手术管理:来自美国大型综合治疗中心的真实世界经验。
Haemophilia. 2021 Jan;27(1):90-99. doi: 10.1111/hae.14212. Epub 2020 Nov 27.
3
Antithrombotic Treatment in Patients With Hemophilia: an EHA-ISTH-EAHAD-ESO Clinical Practice Guidance.
血友病患者的抗血栓治疗:欧洲血液学协会-国际血栓与止血学会-欧洲遗传性血管性水肿协会-欧洲血友病治疗协会临床实践指南
Hemasphere. 2023 Jun 5;7(6):e900. doi: 10.1097/HS9.0000000000000900. eCollection 2023 Jun.
4
Management of children with hemophilia A on emicizumab who need surgery.接受依美珠单抗治疗的需要手术的甲型血友病患儿的管理。
Front Pediatr. 2023 Apr 4;11:1155853. doi: 10.3389/fped.2023.1155853. eCollection 2023.
5
Surgical outcomes in people with hemophilia A taking emicizumab prophylaxis: experience from the HAVEN 1-4 studies.接受艾美赛珠单抗预防治疗的 A 型血友病患者的手术结局:来自 HAVEN 1-4 研究的经验。
Blood Adv. 2022 Dec 27;6(24):6140-6150. doi: 10.1182/bloodadvances.2022007458.
WFH Guidelines for the Management of Hemophilia, 3rd edition.
《血友病管理的居家指南》第三版
Haemophilia. 2020 Aug;26 Suppl 6:1-158. doi: 10.1111/hae.14046. Epub 2020 Aug 3.
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Real-world use of emicizumab in patients with haemophilia A: Bleeding outcomes and surgical procedures.艾美赛珠单抗在血友病 A 患者中的真实世界应用:出血结局和手术操作。
Haemophilia. 2020 Jul;26(4):631-636. doi: 10.1111/hae.14005. Epub 2020 Apr 20.
5
Emicizumab prophylaxis in patients with haemophilia A with and without inhibitors.依库珠单抗预防治疗有和无抑制剂的血友病 A 患者。
Haemophilia. 2020 Jan;26(1):41-46. doi: 10.1111/hae.13877. Epub 2019 Nov 20.
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Blood. 2019 Dec 12;134(24):2127-2138. doi: 10.1182/blood.2019001869.
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Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens.双特异性抗体emicizumab对因子IX/IXa和X/Xa的VIIIa模拟辅因子活性取决于其桥接抗原的能力。
Thromb Haemost. 2017 Jun 28;117(7):1348-1357. doi: 10.1160/TH17-01-0030. Epub 2017 Apr 28.
8
Definitions in hemophilia: communication from the SSC of the ISTH.血友病的定义:来自国际血栓与止血学会(ISTH)科学标准化委员会(SSC)的交流文件
J Thromb Haemost. 2014 Nov;12(11):1935-9. doi: 10.1111/jth.12672. Epub 2014 Sep 3.