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功能性和无功能性肾上腺皮质肿瘤(包括偶发瘤)的诊断与治疗。

Diagnosis and treatment of functioning and nonfunctioning adrenocortical neoplasms including incidentalomas.

作者信息

Thompson N W, Cheung P S

出版信息

Surg Clin North Am. 1987 Apr;67(2):423-36. doi: 10.1016/s0039-6109(16)44193-9.

DOI:10.1016/s0039-6109(16)44193-9
PMID:3551152
Abstract

The most important functional tumors of the adrenal cortex are those that secrete cortisol or aldosterone in excess. Biochemical testing when appropriately utilized can diagnose and differentiate the cause of Cushing's syndrome, and when an adrenal adenoma is found, surgical excision is curative. The diagnosis and surgical treatment of primary aldosteronism are straightforward today, and localization of the usual small cortical tumor producing the syndrome can be achieved by CT and NP-59 scanning or selective venous assays. Adrenocortical carcinomas are relatively rare, are usually incurable when diagnosed, and are an important consideration in the incidentally discovered adrenal mass found by CT scanning.

摘要

肾上腺皮质最重要的功能性肿瘤是那些分泌过量皮质醇或醛固酮的肿瘤。合理运用生化检测可诊断并鉴别库欣综合征的病因,一旦发现肾上腺腺瘤,手术切除可治愈。如今,原发性醛固酮增多症的诊断和外科治疗较为直接,通过CT和NP-59扫描或选择性静脉检测可实现对引发该综合征的常见小皮质肿瘤的定位。肾上腺皮质癌相对罕见,确诊时通常无法治愈,是CT扫描偶然发现的肾上腺肿块时需要重点考虑的情况。

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