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间变性胶质瘤患者术后及放疗期间单药与多药化疗的随机III期试验

Randomized phase III trial of single versus multiple chemotherapeutic treatment following surgery and during radiotherapy for patients with anaplastic gliomas.

作者信息

Mahaley M S, Whaley R A, Krigman M R, Bouldin T W, Bertsch L, Cush S

出版信息

Surg Neurol. 1987 May;27(5):430-2. doi: 10.1016/0090-3019(87)90248-5.

DOI:10.1016/0090-3019(87)90248-5
PMID:3551160
Abstract

In 81 patients with anaplastic supratentorial gliomas, single versus multiple chemotherapeutic agents were selected for treatment following surgery and during radiotherapy in a prospective randomized study. Time to treatment failure and survival were not significantly enhanced by multiple agent chemotherapy, as administered in this study.

摘要

在一项前瞻性随机研究中，对81例幕上间变性胶质瘤患者在手术后及放疗期间选择单一或多种化疗药物进行治疗。如本研究所采用的多药化疗，并未显著延长治疗失败时间和生存期。

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