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潜在肺供体的管理。

Management of the Potential Lung Donor.

机构信息

Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, 500 West Thomas Road, Suite 500, Phoenix, AZ 85013, USA; Creighton University School of Medicine-Phoenix Campus, Phoenix, AZ, USA.

Department of Adult and Pediatric Pathology, University of Messina, Messina, Italy.

出版信息

Thorac Surg Clin. 2022 May;32(2):143-151. doi: 10.1016/j.thorsurg.2021.11.005.

Abstract

The use of donor management protocols has significantly improved recovery rates; however, the inherent instability of lungs after death results in low utilization rates of potential donor lungs. Donor lungs are susceptible to direct trauma, aspiration, neurogenic edema, ventilator-associated barotrauma, and ventilator-associated pneumonia. After irreversible brain injury and determination of futility of care, the goal of medical management of the donor shifts to maintaining hemodynamic stability and maximizing the likelihood of successful organ recovery.

摘要

使用供者管理方案显著提高了回收率;然而,死亡后肺的固有不稳定性导致潜在供者肺的利用率低。供者肺容易受到直接创伤、吸入、神经源性水肿、呼吸机相关性气压伤和呼吸机相关性肺炎的影响。在不可逆性脑损伤和确定治疗无效后,供者的医疗管理目标转变为维持血流动力学稳定和最大限度地提高成功器官恢复的可能性。

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