Additional studies on the therapeutic efficacy of sulphadimidine sodium in experimental Escherichia coli infection of broilers.

In contrast with the recommended dose of 2,000 ppm sulphadimidine sodium in the drinking water for treatment of broilers against colibacillosis, it appeared that under experimental conditions, treatment at 500 ppm (60 mg/kg body weight) gave the best therapeutic effects. At higher concentrations, drinking water consumption and body weight gain were reduced significantly. During treatment high blood plasma-concentrations were measured.